De Novo Centromere Formation: One's Company, Two's a Crowd

被引：0

作者：

Sullivan, Beth A. ^{[1
]}

机构：

[1] Duke Univ, Sch Med, Dept Mol Genet & Microbiol, Div Human Genet, Durham, NC 27710 USA

来源：

DEVELOPMENTAL CELL | 2020年 / 52卷 / 03期

关键词：

DICENTRIC CHROMOSOME;

D O I：

10.1016/j.devcel.2020.01.021

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Chromosomes containing two centromeres (dicentrics) trigger chromosome instability that is avoided by the enigmatic process of centromere inactivation. In this issue of Developmental Cell, Palladino et al. (2020) combine in vivo chromosome engineering and Drosophila genetics to assess consequences of de novo centromere formation and clarify models of centromere inactivation.

引用

页码：257 / 258

页数：2

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