Gefitinib in elderly and unfit patients affected by advanced non-small-cell lung cancer

被引:63
|
作者
Gridelli, C [1 ]
Maione, P
Castaldo, V
Rossi, A
机构
[1] SG Moscati Hosp Via Circumvallaz, Div Med Oncol, I-83100 Avellino, Italy
[2] SG Moscati Hosp Via Circumvallaz, Direz Sanitaria, I-83100 Avellino, Italy
关键词
NSCLC; gefitinib; elderly; poor PS patients;
D O I
10.1038/sj.bjc.6601387
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Elderly and poor performance status advanced non-small-cell lung cancer ( NSCLC) patients often tolerate chemotherapy poorly. Special approaches are needed for these patient populations. Gefitinib ( Iressa) was used in 59 elderly and/or unfit NSCLC pretreated patients participating in a compassionate use programme showing some activity and good tolerability.
引用
收藏
页码:1827 / 1829
页数:3
相关论文
共 50 条
  • [31] Role of Gefitinib in Patients with Non-small-cell Lung Cancer in India
    Mehta, Asmita Anilkumar
    Jose, Wesley M.
    Pavithran, Kicheelath
    Triavadi, Ganesan S.
    INDIAN JOURNAL OF PALLIATIVE CARE, 2013, 19 (01) : 48 - 53
  • [32] Gefitinib in the treatment of elderly patients with advanced non-small cell lung cancer (NSCLC)
    Bearz, Alessandra
    Fratino, Lucia
    Spazzapan, Simon
    Berretta, Massimiliano
    Giacalone, Annalisa
    Simonelli, Cecilia
    Tirelli, Umberto
    LUNG CANCER, 2007, 55 (01) : 125 - 127
  • [33] Gefitinib for the treatment of non-small-cell lung cancer
    Campbell, Lynn
    Blackhall, Fiona
    Thatcher, Nicholas
    EXPERT OPINION ON PHARMACOTHERAPY, 2010, 11 (08) : 1343 - 1357
  • [34] Erlotinib or Gefitinib for Non-Small-Cell Lung Cancer
    Kaye, Frederic J.
    Jantz, Michael A.
    Dallas, Jennifer
    NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (24): : 2367 - 2367
  • [35] Gefitinib for the treatment of non-small-cell lung cancer
    Hida, Toyoaki
    Ogawa, Shizu
    Park, Jang Chul
    Park, Ji Young
    Shimizu, Junichi
    Horio, Yoshitsugu
    Yoshida, Kimihide
    EXPERT REVIEW OF ANTICANCER THERAPY, 2009, 9 (01) : 17 - 35
  • [36] Spotlight on gefitinib in non-small-cell lung cancer
    Frampton, JE
    Easthope, SE
    AMERICAN JOURNAL OF PHARMACOGENOMICS, 2005, 5 (02) : 133 - 136
  • [37] Gefitinib for non-small-cell lung cancer treatment
    D'Incecco, Armida
    Cappuzzo, Federico
    EXPERT OPINION ON DRUG SAFETY, 2011, 10 (06) : 987 - 996
  • [38] Gemcitabine with either paclitaxel or vinorelbine vs paclitaxel or gemcitabine alone for elderly or unfit advanced non-small-cell lung cancer patients
    P Comella
    G Frasci
    P Carnicelli
    B Massidda
    F Buzzi
    G Filippelli
    L Maiorino
    M Guida
    N Panza
    S Mancarella
    R Cioffi
    British Journal of Cancer, 2004, 91 : 489 - 497
  • [39] Gemcitabine with either paclitaxel or vinorelbine vs paclitaxel or gemcitabine alone for elderly or unfit advanced non-small-cell lung cancer patients
    Comella, P
    Frasci, G
    Carnicelli, P
    Massidda, B
    Buzzi, F
    Filippelli, G
    Maiorino, L
    Guida, M
    Panza, N
    Mancarella, S
    Cioffi, R
    BRITISH JOURNAL OF CANCER, 2004, 91 (03) : 489 - 497
  • [40] Docetaxel as monotherapy in the treatment of advanced non-small-cell lung cancer in elderly patients
    Malani, Ashok K.
    Abou-Jawde, Rony M.
    Singh, Jaswinder
    Taylor, Sarah A.
    JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (09) : 1143 - 1144