Catalyst-Controlled 1,2-and 1,1-Arylboration of -Alkyl Alkenyl Arenes

被引：79

作者：

Bergmann, Allison M. ^{[1
]}

Dorn, Stanna K. ^{[1
]}

Smith, Kevin B. ^{[1
]}

Logan, Kaitlyn M. ^{[1
]}

Brown, M. Kevin ^{[1
]}

机构：

[1] Indiana Univ, Dept Chem, 800 E Kirkwood Ave, Bloomington, IN 47405 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2019年 / 58卷 / 06期

关键词：

carboboration; copper; cross-coupling; homogeneous catalysis; palladium; CROSS-COUPLING REACTIONS; ENANTIOSELECTIVE ARYLBORATION; REGIOSELECTIVE ARYLBORATION; ARYL BROMIDES; TERTIARY; COPPER; COMPLEXES; REAGENTS; 1,1-DIARYLATION; SECONDARY;

D O I：

10.1002/anie.201812533

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two methods are reported for the 1,2- and 1,1-arylboration of -methyl vinyl arenes. In the case of 1,2-arylboration, the formation of a quaternary center occurred through a rare cross-coupling reaction of a tertiary organometallic complex. 1,1-Arylboration was enabled by catalyst optimization and occurred through a -hydride elimination/reinsertion cascade. Enantioselective variants of both processes are presented as well as mechanistic investigations.

引用

页码：1719 / 1723

页数：5

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