Polyunsaturated Fatty Acids and Their Potential Therapeutic Role in Cardiovascular System Disorders-A Review

被引:232
|
作者
Sokola-Wysoczanska, Ewa [1 ]
Wysoczanski, Tomasz [2 ]
Wagner, Jolanta [2 ,3 ]
Czyz, Katarzyna [4 ]
Bodkowski, Robert [4 ]
Lochynski, Stanislaw [3 ,5 ]
Patkowska-Sokola, Bozena [4 ]
机构
[1] Lumina Cordis Fdn, Szymanowskiego St 2-A, PL-51609 Wroclaw, Poland
[2] FLC Pharma Ltd, Wroclaw Technol Pk,Muchoborska St 18, PL-54424 Wroclaw, Poland
[3] Univ Technol, Fac Chem, Dept Bioorgan Chem, Wybrzeze Wyspianskiego St 27, PL-50370 Wroclaw, Poland
[4] Wroclaw Univ Environm & Life Sci, Fac Biol & Anim Sci, Inst Anim Breeding, Chelmonskiego St 38c, PL-50001 Wroclaw, Poland
[5] Wroclaw Coll Physiotherapy, Inst Cosmetol, Kosciuszki 4 St, PL-50038 Wroclaw, Poland
关键词
cardiovascular system; omega-3 fatty acids; alpha-linoleic acid (ALA); eicosapentaenoic acid (EPA); docosahexaenoic acid (DHA); lipids; nutrition; ALPHA-LINOLENIC ACID; PERCUTANEOUS CORONARY INTERVENTION; LONG-CHAIN OMEGA-3-FATTY-ACIDS; DUAL ANTIPLATELET THERAPY; FISH-OIL; MYOCARDIAL-INFARCTION; DOCOSAHEXAENOIC ACID; DOUBLE-BLIND; HEART-DISEASE; ATRIAL-FIBRILLATION;
D O I
10.3390/nu10101561
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Cardiovascular diseases are described as the leading cause of morbidity and mortality in modern societies. Therefore, the importance of cardiovascular diseases prevention is widely reflected in the increasing number of reports on the topic among the key scientific research efforts of the recent period. The importance of essential fatty acids (EFAs) has been recognized in the fields of cardiac science and cardiac medicine, with the significant effects of various fatty acids having been confirmed by experimental studies. Polyunsaturated fatty acids are considered to be important versatile mediators for improving and maintaining human health over the entire lifespan, however, only the cardiac effect has been extensively documented. Recently, it has been shown that omega-3 fatty acids may play a beneficial role in several human pathologies, such as obesity and diabetes mellitus type 2, and are also associated with a reduced incidence of stroke and atherosclerosis, and decreased incidence of cardiovascular diseases. A reasonable diet and wise supplementation of omega-3 EFAs are essential in the prevention and treatment of cardiovascular diseases prevention and treatment.
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页数:21
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