Recombinant antibody potently neutralizes types A, B, and E botulinum neurotoxins by a clearancedriven mechanism

被引：0
|
作者：
Marks, James
Garcia, Consuelo [1 ]
Geren, Isin N. [1 ]
Lou, Jianlong [1 ]
Forsyth, Charles M. [1 ]
Fraser, Conrad [1 ]
Wen, Weihua [1 ]
Smith, Theresa J. [2 ]
Brown, Jennifer [2 ]
Al-Saleem, Fetweh [3 ]
Ancharski, Denise [3 ]
Simpson, Lance L. [3 ]
Tepp, William H. [4 ]
Johnson, Eric A. [4 ]
Smith, Leonard A. [2 ]
机构：
[1] Univ Calif San Francisco, Dept Anesthesia & Pharmaceut Chem, San Francisco, CA 94143 USA
[2] USA, Med Inst Infect Dis, Integrated Toxicol Div, Ft Detrick, MD USA
[3] Thomas Jefferson Univ, Jefferson Med Coll, Dept Med, Philadelphia, PA 19107 USA
[4] Univ Wisconsin, Dept Food Microbiol & Toxicol, Madison, WI 53706 USA
来源：
TOXICON | 2008年 / 51卷
关键词：
botulism; antitoxin; monoclonal antibody;
D O I：
10.1016/j.toxicon.2008.04.152
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
150
引用
收藏
页码：50 / 50
页数：1
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