Recombinant antibody potently neutralizes types A, B, and E botulinum neurotoxins by a clearancedriven mechanism

被引：0

作者：

Marks, James

Garcia, Consuelo ^{[1
]}

Geren, Isin N. ^{[1
]}

Lou, Jianlong ^{[1
]}

Forsyth, Charles M. ^{[1
]}

Fraser, Conrad ^{[1
]}

Wen, Weihua ^{[1
]}

Smith, Theresa J. ^{[2
]}

Brown, Jennifer ^{[2
]}

Al-Saleem, Fetweh ^{[3
]}

Ancharski, Denise ^{[3
]}

Simpson, Lance L. ^{[3
]}

Tepp, William H. ^{[4
]}

Johnson, Eric A. ^{[4
]}

Smith, Leonard A. ^{[2
]}

机构：

[1] Univ Calif San Francisco, Dept Anesthesia & Pharmaceut Chem, San Francisco, CA 94143 USA

[2] USA, Med Inst Infect Dis, Integrated Toxicol Div, Ft Detrick, MD USA

[3] Thomas Jefferson Univ, Jefferson Med Coll, Dept Med, Philadelphia, PA 19107 USA

[4] Univ Wisconsin, Dept Food Microbiol & Toxicol, Madison, WI 53706 USA

来源：

TOXICON | 2008年 / 51卷

关键词：

botulism; antitoxin; monoclonal antibody;

D O I：

10.1016/j.toxicon.2008.04.152

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

150

引用

页码：50 / 50

页数：1

共 50 条

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