Influence of gut microbiota and intestinal barrier on enterogenic infection after liver transplantation

被引：27
|
作者：
Mu, Jingzhou [1 ]
Chen, Qiuyu [1 ]
Zhu, Liang [1 ]
Wu, Yunhong [2 ]
Liu, Suping [1 ]
Zhao, Yufei [1 ]
Ma, Tonghui [1 ]
机构：
[1] Dalian Med Univ, Coll Basic Med, Dalian, Liaoning, Peoples R China
[2] Dalian Med Univ, Coll Publ Hlth, Dalian, Liaoning, Peoples R China
来源：
CURRENT MEDICAL RESEARCH AND OPINION | 2019年 / 35卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Liver transplantation; complication; enterogenic infection; gut microbiota; bacterial translocation; intestinal barrier function; CLOSTRIDIUM-DIFFICILE INFECTION; RISK-FACTORS; BACTERIAL TRANSLOCATION; DOUBLE-BLIND; DONOR; COMPLICATIONS; HEALTH; PROBIOTICS; CIRRHOSIS; TRIAL;
D O I：
10.1080/03007995.2018.1470085
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Liver transplantation is currently a standard therapy for patients with end-stage liver diseases and hepatocellular carcinoma. Given that liver transplantation has undergone a thriving development in these decades, the survival rates after liver transplantation have markedly improved as a result of the critical advancement in surgical techniques, immunosuppressive therapies, and post-operative care. However, infection remains a fatal complication after liver transplantation surgery. In particular, enterogenic infection represents a major complication in liver transplant recipients. This article gives an overview of infection cases after liver transplantation and focuses on the discussion of enterogenic infection in terms of its pathophysiology, risk factor, outcome, and treatment.
引用
收藏
页码：241 / 248
页数：8
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