BACKGROUND Pulmonary vein isolation (PVI) is an established treatment option for atrial fibrillation (AF). Recently the novel endoscopic ablation system (EAS) was introduced and proved potential for successful acute PVI. OBJECTIVE This study sought to investigate the 1-year follow-up results after EAS-based PVI. METHODS A total of 40 patients (20 female, age 57 +/- 9 years) with a long history (5 +/- 4 years) of drug-refractory (2 +/- 1 antiarrhythmic drugs) paroxysmal AF were included into our analysis. PVI was performed using exclusively the novel EAS. Follow-up included regular telephonic interviews, Holter electrocardiographic (ECG) and transtelephonic ECG recordings. A symptomatic or documented AF episode > 60 seconds after a blanking period of 3 months was defined as recurrence. RESULTS A total of 155 PVs were targeted; 153 of 155 (99%) PVs were isolated successfully using exclusively the novel EAS. During a median follow-up of 402 (331 to 478; quartile 1 to quartile 3) days, 24 of 40 patients (60%) remained free of any symptomatic or documented AF episode without antiarrhythmic drugs after a single procedure. Seven patients suffering from AF recurrence underwent radiofrequency current-based Re-PVI 203 +/- 102 days after the index EAS-based procedure. Left atrium to pulmonary vein reconduction was found in 17 of 25 initially isolated PVs. No PV stenosis was detected based on magnetic resonance imaging 3 months postablation. CONCLUSION Patients after EAS-based PVI due to paroxysmal AF demonstrate 1-year single-procedure success rates similar to those of other ablation techniques and ablation energies. The major determinant for AF recurrence after EAS treatment seems to be reconnection of previously isolated PVs. More patients and longer follow-up periods are mandatory before final conclusions can be drawn regarding the efficacy and safety of the EAS.
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Gen Hosp Northern Theater Command, Shenyang, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Wang, Zulu
Tang, Min
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Chinese Acad Med Sci & Peking Union Med Coll, Fuwai Hosp, Beijing, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Tang, Min
Reddy, Vivek Y.
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Icahn Sch Med Mt Sinai, New York, NY USAGen Hosp Northern Theater Command, Shenyang, Peoples R China
Reddy, Vivek Y.
Chu, Huimin
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Ningbo First Hosp, Ningbo, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Chu, Huimin
Liu, Xingpeng
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Capital Med Univ, Beijing Chaoyang Hosp, Beijing, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Liu, Xingpeng
Xue, Yumei
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Guangdong Prov Peoples Hosp, Guangzhou, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Xue, Yumei
Wang, Jingfeng
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Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, South Campus Outpatient Clin, Guangzhou, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Wang, Jingfeng
Xu, Jing
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Tianjin Chest Hosp, Tianjin, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Xu, Jing
Liu, Shaowen
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Shanghai First Peoples Hosp, Shanghai, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Liu, Shaowen
Xu, Wei
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Nanjing Drum Tower Hosp, Nanjing, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Xu, Wei
Zhang, Zhihui
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Cent South Univ, Xiangya Hosp 3, Changsha, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Zhang, Zhihui
Han, Bing
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Xuzhou Cent Hosp, Xuzhou, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Han, Bing
Hong, Lang
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Jiangxi Prov Peoples Hosp, Nanchang, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Hong, Lang
Yang, Bing
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Shanghai East Hosp, Shanghai, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
Yang, Bing
Liang, Ming
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Gen Hosp Northern Theater Command, Shenyang, Peoples R ChinaGen Hosp Northern Theater Command, Shenyang, Peoples R China
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Third Mil Med Univ, Xinqiao Hosp, Cardiovasc Dept, Chongqing, Peoples R ChinaThird Mil Med Univ, Xinqiao Hosp, Cardiovasc Dept, Chongqing, Peoples R China