Synthesis of (1R,1R')-2,6-bis[1-(diphenylphosphino)ethyl]pyridine and its application in asymmetric transfer hydrogenation

被引：117
|
作者：
Jiang, QZ [1 ]
VanPlew, D [1 ]
Murtuza, S [1 ]
Zhang, XM [1 ]
机构：
[1] PENN STATE UNIV,DEPT CHEM,UNIVERSITY PK,PA 16802
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 06期
关键词：
D O I：
10.1016/0040-4039(95)02298-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A C-2 symmetric tridentate ligand, (1R, 1R') 2,6-Bis[1-(diphenylphosphino)ethyl]pyridine, has been synthesized in enantiomerically pure form. A practical method to synthesize a variety of chiral pyridyl diols is reported. Asymmetric transfer hydrogenation is achieved using the tridentate ligand.
引用
收藏
页码：797 / 800
页数：4
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