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Guangzhou Med Univ, Dept Allergy & Clin Immunol, State Key Lab Resp Dis,Guangzhou Inst Resp Hlth, Affiliated Hosp 1,Natl Clin Res Ctr Resp Dis, Guangzhou, Guangdong, Peoples R China Guangzhou Med Univ, Dept Allergy & Clin Immunol, State Key Lab Resp Dis,Guangzhou Inst Resp Hlth, Affiliated Hosp 1,Natl Clin Res Ctr Resp Dis, Guangzhou, Guangdong, Peoples R China