MicroRNAs, damage levels, and DNA damage response control

被引：5
|
作者：
Visser, Hartwig [1 ]
Thomas, Adam D. [1 ]
机构：
[1] Univ West England, Ctr Res Biosci, Coldharbour Lane, Bristol BS16 1QY, Avon, England
来源：
TRENDS IN GENETICS | 2021年 / 37卷 / 11期
关键词：
P53; ATM; PHOSPHORYLATION; INDUCTION;
D O I：
10.1016/j.tig.2021.06.018
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
DNA damage-inducible miRNAs are likely to be functional in the DNA damage response. This response can elicit damage resolution and cell survival or apoptosis. The current, albeit incomplete, picture suggests that miRNAs can affect cell fate via modulation of key response proteins, but the question is, who's in charge?
引用
收藏
页码：963 / 965
页数：3
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