MicroRNAs, damage levels, and DNA damage response control

被引：5
|
作者：
Visser, Hartwig [1 ]
Thomas, Adam D. [1 ]
机构：
[1] Univ West England, Ctr Res Biosci, Coldharbour Lane, Bristol BS16 1QY, Avon, England
来源：
TRENDS IN GENETICS | 2021年 / 37卷 / 11期
关键词：
P53; ATM; PHOSPHORYLATION; INDUCTION;
D O I：
10.1016/j.tig.2021.06.018
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
DNA damage-inducible miRNAs are likely to be functional in the DNA damage response. This response can elicit damage resolution and cell survival or apoptosis. The current, albeit incomplete, picture suggests that miRNAs can affect cell fate via modulation of key response proteins, but the question is, who's in charge?
引用
收藏
页码：963 / 965
页数：3
相关论文
共 50 条
  • [1] MicroRNAs, DNA damage response and ageing
    Majidinia, Maryam
    Mir, Seyed Mostafa
    Mirza-Aghazadeh-Attari, Mohammad
    Asghari, Roghaieh
    Kafil, Hossein Samadi
    Safa, Amin
    Mahmoodpoor, Ata
    Yousefi, Bahman
    BIOGERONTOLOGY, 2020, 21 (03) : 275 - 291
  • [2] MicroRNAs, DNA damage response and ageing
    Maryam Majidinia
    Seyed Mostafa Mir
    Mohammad Mirza-Aghazadeh-Attari
    Roghaieh Asghari
    Hossein Samadi Kafil
    Amin Safa
    Ata Mahmoodpoor
    Bahman Yousefi
    Biogerontology, 2020, 21 : 275 - 291
  • [3] MicroRNAs, the DNA damage response and cancer
    Wouters, Maikel D.
    van Gent, Dik C.
    Hoeijmakers, Jan H. J.
    Pothof, Joris
    MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2011, 717 (1-2) : 54 - 66
  • [4] MicroRNAs: new players in the DNA damage response
    Hu, Hailiang
    Gatti, Richard A.
    JOURNAL OF MOLECULAR CELL BIOLOGY, 2011, 3 (03) : 151 - 158
  • [5] MicroRNAs, DNA Damage Response, and Cancer Treatment
    He, Mingyang
    Zhou, Weiwei
    Li, Chuang
    Guo, Mingxiong
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 17 (12):
  • [6] Identification of microRNAs that regulate DNA damage response
    Wang, Yemin
    Taniguchi, Toshiyasu
    CANCER RESEARCH, 2010, 70
  • [7] MicroRNAs in DNA Damage Response, Carcinogenesis, and Chemoresistance
    Fang, Yuanzhang
    Zhang, Lu
    Li, Zhenghu
    Li, Yujing
    Huang, Cheng
    Lu, Xiongbin
    MIRNAS IN DIFFERENTIATION AND DEVELOPMENT, 2017, 333 : 1 - 49
  • [8] Crosstalk between the DNA damage response pathway and microRNAs
    Cecil Han
    Guohui Wan
    Robert R. Langley
    Xinna Zhang
    Xiongbin Lu
    Cellular and Molecular Life Sciences, 2012, 69 : 2895 - 2906
  • [9] Crosstalk between the DNA damage response pathway and microRNAs
    Han, Cecil
    Wan, Guohui
    Langley, Robert R.
    Zhang, Xinna
    Lu, Xiongbin
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2012, 69 (17) : 2895 - 2906
  • [10] MicroRNAs and DNA damage response Implications for cancer therapy
    Wang, Yemin
    Taniguchi, Toshiyasu
    CELL CYCLE, 2013, 12 (01) : 32 - 42
12345