Advances in the clinical laboratory assessment of urinary sediment

被引:19
|
作者
Chan, RWY [1 ]
Szeto, CC [1 ]
机构
[1] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut, Shatin, Hong Kong, Peoples R China
关键词
kidney; urinalysis; flow cytometry; urology;
D O I
10.1016/j.cccn.2003.11.006
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Urinalysis has been used extensively in clinical practice to aid in the diagnosis of various renal and urologic diseases. The innovation of urinalysis is marching on right along with the rapid developments in biotechnology and astride from the solo urine cytology to sophisticated studies of individual component in the urinary sediment. In this review article, we focus on the use of flow cytometry and other technical advances in the examination of urinary sediment, the detection of urologic malignancies by the presence of microsatellite alteration in the urinary sediment, as well as the quantification of cytokine messenger RNA (mRNA) expression in urinary sediment by reverse transcription and real-time quantitative polymerase chain reaction (RT-QPCR). Notably, the study of cytokine mRNA expression in urinary sediment by RT-QPCR has recently been reported to provide important diagnostic information in kidney allograft recipients and patients with lupus nephritis. This simple and non-invasive method requires further study to determine its role in risk stratification and monitoring of therapeutic response in patients with other kidney diseases. (C) 2003 Elsevier B.V. All rights reserved.
引用
收藏
页码:67 / 78
页数:12
相关论文
共 50 条
  • [21] CLINICAL LABORATORY ESTIMATIONS OF SERUM AND URINARY PHOSPHATE
    BURKHARDT, RT
    SHEIKO, MC
    BATSAKIS, JG
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1979, 72 (02) : 326 - 329
  • [22] ASSESSMENT OF CLINICAL LABORATORY CAPABILITY
    不详
    MEDICAL JOURNAL OF AUSTRALIA, 1974, 2 (16) : 585 - 586
  • [23] CLINICAL LABORATORY DIAGNOSIS OF URINARY TRACT INFECTIONS
    SENECA, H
    PEER, P
    JOURNAL OF UROLOGY, 1965, 94 (01): : 78 - &
  • [24] URINARY DISEASES AND CLINICAL BIOCHEMISTRY LABORATORY PROCEDURES
    BRAUN, JP
    MEDAILLE, C
    RICO, AG
    RECUEIL DE MEDECINE VETERINAIRE, 1988, 164 (11) : 889 - 900
  • [25] URINARY OXYGEN TENSION - LABORATORY AND CLINICAL OBSERVATIONS
    MARTIN, DC
    INVESTIGATIVE UROLOGY, 1968, 5 (06): : 580 - &
  • [26] An Italian External Quality Assessment (EQA) program on urinary sediment
    Fogazzi, Giovanni B.
    Secchiero, Sandra
    Consonni, Dario
    Sciacovelli, Laura
    Zardo, Lorena
    Garigali, Giuseppe
    Verdesca, Simona
    Messa, Piergiorgio
    Plebani, Mario
    CLINICA CHIMICA ACTA, 2010, 411 (11-12) : 859 - 867
  • [27] EFFECTS OF SUSPENDED SEDIMENT ON FISH EGGS AND LARVAE - LABORATORY ASSESSMENT
    AULD, AH
    SCHUBEL, JR
    ESTUARINE AND COASTAL MARINE SCIENCE, 1978, 6 (02): : 153 - 164
  • [28] ADVANCES IN DIAGNOSIS AND CLINICAL LABORATORY TESTING IN IMMUNOLOGICAL DISORDERS
    HICKS, MJ
    JONES, JF
    ARIZONA MEDICINE, 1981, 38 (06) : 438 - 443
  • [29] TECHNOLOGY IN BIOMEDICAL INSTRUMENTATION: CLINICAL AND LABORATORY ADVANCES.
    HAMER, LOUIS
    1982, V 29 (N 9) : 101 - 103
  • [30] RECENT ADVANCES IN THE CLINICAL HEMATOLOGY LABORATORY - DIAGNOSIS OF ANEMIA
    BIERMAN, AH
    JOURNAL OF THE FLORIDA MEDICAL ASSOCIATION, 1980, 67 (02): : 107 - 110