Synthesis and evaluation of cytotoxic activity of novel arylsulfonylimidazolidinones

被引：33
|
作者：
Jung, SH [1 ]
Song, JS [1 ]
Lee, HS [1 ]
Choi, SU [1 ]
Lee, CO [1 ]
机构：
[1] KOREA RES INST CHEM TECHNOL,TAEJON 305343,SOUTH KOREA
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 21期
关键词：
D O I：
10.1016/0960-894X(96)00463-5
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Synthesis of novel arylsulfonylimidazolidinones 3 and 4 containing sulfonylurea pharmacophore and evaluation of their in vitro cytotoxicity against human cell lines were investigated. As a result, a series of 4-phenyl-1(N)-arylsulfonylimidazolidinones have been found to be the potential anticancer agent. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码：2553 / 2558
页数：6
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