Study of substrate dependence on the diastereoselectivity of the ruthenium(II) porphyrin catalyzed tandem formation and 1,3-dipolar cycloaddition reactions of carbonyl ylides

被引：0
|
作者：
Zhou, CY
Chan, PWH
Yu, WY
Che, CM
机构：
[1] Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China
[2] Univ Hong Kong, Open Lab Chem Biol, Inst Mol Technol Drug Discovery & Synth, Hong Kong, Hong Kong, Peoples R China
来源：
SYNTHESIS-STUTTGART | 2003年 / 09期
关键词：
carbonyl ylide formation; 1,3-dipolar cycloaddition; metallocarbenoids; rhodium(II; II); dimers; ruthenium(II) porphyrins;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The effect of substrate substitution on reaction selectivity for the ruthenium(II) porphyrin catalyzed tandem carbonyl ylide formation/1,3-dipolar cycloaddition reaction of a variety of alkyl and aryl substituted alpha-diazo ketones 1 with pi-unsaturated compounds was examined. The results suggested the diastereoselectivity of the reaction to be highly substrate dependant. Similar yields and cis/trans selectivities have also been achieved for the analogous reactions with rhodium(II,II) dimer as catalyst.
引用
收藏
页码：1403 / 1412
页数：10
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