Method of synthesis and structure of (5E)-5-(2-alkoxy-2-oxoethylidene)-4-hydroxy-2,2-dimethyl-1-(4-methylphenyl)-2,5-dihydro-1H-pyrrole-3-carboxylates

被引：6
|
作者：
Mukovoz, P. P. [1 ,2 ]
Koz'minykh, V. O. [2 ,3 ]
Andreeva, V. A. [3 ]
El'tsov, O. S. [4 ]
Slepukhin, P. A. [5 ]
Koz'minykh, E. N. [2 ]
机构：
[1] Russian Acad Sci, Ural Branch, Inst Cellular & Intracellular Symbiosis, Orenburg 460000, Russia
[2] Perm State Humanitarian Pedag Univ, Perm 614990, Russia
[3] Orenburg State Univ, Orenburg 460018, Russia
[4] Yeltsin Ural Fed Univ, Ekaterinburg 620002, Russia
[5] Russian Acad Sci, Ural Branch, Postovskii Inst Organ Synth, Ekaterinburg 620990, Russia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 51卷 / 06期
关键词：
Schiff Base; Oxazine; Ethylidene; Dioxo; Dienol;
D O I：
10.1134/S107042801506007X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A procedure has been developed for the synthesis of dialkyl (5E)-5-(2-alkoxy-2-oxoethylidene)-4-hydroxy-2,2-dimethyl-1-(4-methylphenyl)-2,5-dihydro-1H-pyrrole-3-carboxylates by three-component condensation of dialkyl 3,4-dihydroxyhexa-2,4-dienedioate with acetone and p-toluidine. The structure of the products is discussed on the basis of the IR, H-1 NMR, and X-ray diffraction data.
引用
收藏
页码：860 / 863
页数：4
相关论文
共 50 条
  • [31] Crystal structure of 5-(1-benzofuran-2-yl)-3-(4-methylphenyl)-4,5-dihydro-1,2-oxazol-5-ol
    Ravi, A. J.
    Vinayaka, A. C.
    Jeyaseelan, S.
    Sadashiva, M. P.
    Devarajegowda, H. C.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2015, 71 : O492 - U363
  • [32] (RS,RS)-5-[hydroxy(4-methylphenyl)-methyl]furan-2(5H)-one
    Ollevier, Thierry
    Bouchard, Jean-Emmanuel
    Desyroy, Valerie
    Tessier, Christian
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O4298 - U3186
  • [33] Synthesis of 5-(4-hydroxy-3-methylphenyl)-5-(substitutedphenyl)-4, 5-dihydro-1H-1-pyrazolyl-4-pyridylmethanone derivatives with anti-viral activity
    Ali, Mohamed Ashraf
    Shaharyar, Mohammad
    De Clercq, Erick
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2007, 22 (06) : 702 - 708
  • [34] INFLUENCE OF 2,2-DIMETHYL-1-(4-METHYLPHENYL)-1-PROPANONE (SAH 50-283) ON FOOD EFFICIENCY IN RATS
    HO, RS
    ARANDA, CG
    ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE, 1979, 237 (01): : 98 - 109
  • [35] Crystal structure of 5-[4-(dimethylamino)phenyl]-3-(4-methylphenyl)-4,5dihydro-1H-pyrazole-1-carbaldehyde
    Adam, Farook
    Samshuddin, Seranthimata
    Ameram, Nadiah
    Subramaya
    Samartha, Laxminarayana
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2015, 71 : O1031 - U1147
  • [36] (4-Methylphenyl)[1-(4-methylphenyl)-3-(5-nitro-2-furyl)-1H-pyrazol-4-yl]methanone
    Goh, Jia Hao
    Fun, Hoong-Kun
    Nithinchandra
    Rai, N. Satheesh
    Kalluraya, B.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O3099 - U667
  • [37] (E)-N-(4-Chlorobenzylidene)-5-(4-methylphenyl)-1,3,4-thiadiazol-2-amine
    Yu, Peng
    Wang, Peng
    Zhang, Jian-Qiang
    He, Qiu
    Wan, Rong
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O861 - U400
  • [38] 3-(4-Methylphenyl)-5-[4-(methylthio)phenyl]-4,5-dihydro-1H-pyrazole-1-carbaldehyde
    Butcher, Ray J.
    Jasinski, Jerry P.
    Prasad, D. Jagadeesh
    Narayana, B.
    Yathirajan, H. S.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O4005 - U2625
  • [39] STRUCTURE OF DIETHYL 2,6-DIMETHYL-4-[5-(4-METHYLPHENYL)-2-FURYL]-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE
    LOKAJ, J
    VRABEL, V
    SIVY, P
    KETTMANN, V
    ILAVSKY, D
    JECNY, J
    ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 1991, 47 : 886 - 888
  • [40] Condensation of 5-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione with haloacetic acids
    Rzhevskii, A. A.
    Gerasimova, N. P.
    Alov, E. M.
    Kozlova, O. S.
    Danilova, A. S.
    Khapova, S. A.
    Suponitskii, K. Yu.
    RUSSIAN CHEMICAL BULLETIN, 2012, 61 (11) : 2133 - 2136
12345