General biological aspects of oncogenesis

被引：0
|
作者：
D'Amato, G [1 ]
Patarca, R [1 ]
机构：
[1] Jackson Mem Hosp, Dept Internal Med, Miami, FL 33136 USA
来源：
CRITICAL REVIEWS IN ONCOGENESIS | 1998年 / 9卷 / 3-4期
关键词：
tumor suppressor genes; oncogenes; metastasis;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Both genetic and epigenetic events play an important role in oncogenic processes. This review discusses the four hypothesis for the origin of neoplastic transformation (mutational genetic, nonmutational genetic, viral, and epigenetic) in the context of a summary of our current knowledge of the pathobiology of cancer.
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页码：275 / 373
页数：99
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