Oxidative cyclization of β-hydroxyenones with palladium(II):: A novel entry to 2,3-dihydro-4H-pyran-4-ones

被引：54
|
作者：
Reiter, M [1 ]
Ropp, S [1 ]
Gouverneur, V [1 ]
机构：
[1] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England
来源：
ORGANIC LETTERS | 2004年 / 6卷 / 01期
关键词：
D O I：
10.1021/ol0361296
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A palladium(II)-mediated oxidative cyclization was found to be effective for the preparation of structurally diverse 2,3-dihydro-4H-pyran-4-ones from the corresponding beta-hydroxyenones. Attractive features of this transformation include the ready availability of the starting enones, the regiocontrol, and the easy access of enantiopure 2,3-dihydro-4H-pyran-4-one from the corresponding enantiopure enone.
引用
收藏
页码：91 / 94
页数：4
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