PET/CT imaging in inflammatory myopathies

被引:17
|
作者
Al-Nahhas, Adil [1 ]
Jawad, Ali S. M. [2 ]
机构
[1] Imperial Coll NHS Trust, Nucl Med Serv, Hammersmith Hosp, Dept Nucl Med, London W12 0HS, England
[2] Royal London Hosp, Dept Rheumatol, London E1 1BB, England
关键词
FDG PET/CT; inflammatory myopathy; polymyositis; dermatomyositis; POSITRON-EMISSION-TOMOGRAPHY; SIGNAL RECOGNITION PARTICLE; INCLUSION-BODY MYOSITIS; LARGE-VESSEL VASCULITIS; FDG-PET; PARANEOPLASTIC SYNDROMES; FLUORODEOXYGLUCOSE-PET; F-18-FDG UPTAKE; UNKNOWN ORIGIN; DERMATOMYOSITIS;
D O I
10.1111/j.1749-6632.2011.06016.x
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Inflammatory muscle diseases are a group of muscle disorders characterized by muscle weakness, fatigue, and an association with malignancy and paraneoplastic syndrome. A diagnosis of idiopathic inflammatory myopathy is suggested by abnormal myometry and rising creatine kinase, but tissue diagnosis is also needed. Magnetic resonance imaging (MRI) helps localize the appropriate site of biopsy, demonstrate the extent of muscle involvement, and monitor the response to therapy. However, the sensitivity of magnetic resonance (MR) is limited, and whole-body imaging is still far from routine. [F-18]Fluoro-desoxy-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) is currently the ultimate metabolic imaging technique for the management of cancer. It has also been shown to detect inflammatory conditions and to monitor their response to treatment. The use of FDG PET in screening for underlying malignancies is widely reported and recommended in patients with paraneoplastic syndrome. Unfortunately, only a few reports have been published to show the value of FDG PET in inflammatory muscle diseases, which as we show herein, deserve further pursuit.
引用
收藏
页码:39 / 45
页数:7
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