Fabrication of 3D Electrospun Polycaprolactone Sponge Incorporated with Pt@AuNPs for Biomedical Applications

被引:6
|
作者
Jaswal, Richa [1 ,3 ]
Hwang, Tae In [2 ,3 ]
Kumar, Dinesh [3 ]
Lee, Jeong Chan [3 ]
Park, Chan Hee [1 ,3 ]
Kim, Cheol Sang [1 ,3 ]
机构
[1] Jeonbuk Natl Univ, Div Mech Design Engn, Jeonju 561756, Jeonbuk, South Korea
[2] Woori Convalescent Hosp Jeonju, Dept Med Practicing, Jeonbuk 54914, South Korea
[3] Jeonbuk Natl Univ, Dept Bionanosyst Engn, Jeonju 561756, Jeonbuk, South Korea
基金
新加坡国家研究基金会;
关键词
Core-Satellite Nanoparticles; 3D Scaffold; Electro-Spinning; HR-TEM; Bone Tissue Engineering;
D O I
10.1166/jnn.2020.17563
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Here, we report the synthesis of three-dimensional (3D) polycaprolactone (PCL) nanofiber incorporated with core-satellite platinum nanoparticles (PtNPs, 2-3 nm) coated gold nanospheres (AuNPs, 30 nm) via the simple lactic acid assisted self-assembly electrospinning technique. The Pt-AuNPs nanoparticle in core-satellite form has been prepared by following solution based methods and characterized with TEM, HR-TEM, UV-Visible, and XRD spectroscopic techniques. The surface morphology and structural analysis of 3D nanofiber scaffolds have been performed with FTIR, TGA, FESEM, and HR-TEM analysis techniques and shown the successful preparation of 3D electrospun fibrous structure composed of Pt-AuNPs loaded PCL (PCL@Pt-AuNPs) as a potential biomaterial for bone tissue engineering applications.
引用
收藏
页码:3989 / 3993
页数:5
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