Differential expression of the zinc finger gene Zfp105 during spermatogenesis

被引：4
|
作者：
Przyborski, SA
Knowles, BB
Handel, MA
Gurwitch, SA
Ackerman, SL
机构：
[1] Jackson Lab, Bar Harbor, ME 04609 USA
[2] Univ Tennessee, Dept Biochem & Cellular & Mol Biol, Knoxville, TN 37996 USA
来源：
MAMMALIAN GENOME | 1998年 / 9卷 / 09期
关键词：
D O I：
10.1007/s003359900859
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We report the isolation of Zfp105, the mouse homolog of the human ZNF35 zinc finger gene. Zfp105 and ZNF35 are highly conserved at the protein and nucleotide level, and Zfp105 maps to a region of mouse Chromosome (Chr) 9 that is homologous to the human region containing ZNF35. Zpf105 is highly expressed in the testis, especially in pachytene spermatocytes and round spermatids. The possible role of this gene product in maintaining an ordered germ cell differentiation process is discussed.
引用
收藏
页码：758 / 762
页数：5
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