An Efficient Route to Imidazo[1,2-a]Pyridines and Pyrido[1,2-a]Pyrimidines via One-Pot Four-Component Reaction Using Fe3O4-GO-SO3H

被引:3
|
作者
Karimiyan, Asiyeh [1 ]
Rostamizadeh, Shahnaz [1 ]
机构
[1] KN Toosi Univ Technol, Dept Chem, Tehran, Iran
关键词
1,4-Dihydropyridine; magnetic graphene oxide; multicomponent reactions; nitrogen heterocycles; spiro-oxindole; HETEROCYCLIC KETENE AMINALS; MULTICOMPONENT SYNTHESIS; 3-COMPONENT REACTION; CASCADE REACTION; IONIC LIQUID; CATALYST; FUNCTIONALIZATION; DERIVATIVES; DESIGN; DOMINO;
D O I
10.1080/10406638.2019.1686400
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient, one-pot synthetic protocol toward 1,4-dihydropyridine derivatives starting from 1,1-bis(methylthio)-2-nitroethylene, 1,n-diamine, malononitriles, and either isatins or aromatic aldehydes has been developed. The reaction proceeds under solvent-free conditions in the presence of nano-Fe3O4-GO-SO3H as a solid acidic catalyst to give the title compounds in good yields. [GRAPHICS] Sulfonic functionalized magnetic graphene oxide catalyzed one-pot four components synthesis of 1,4-dihydropyridine derivatives under solvent-free conditions.
引用
收藏
页码:1483 / 1494
页数:12
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