Cytokine and chemokine response in children with the 2009 pandemic influenza A (H1N1) virus infection

被引：42
|
作者：
Takano, T. [1 ]
Tajiri, H. [1 ]
Kashiwagi, Y. [2 ]
Kimura, S. [1 ]
Kawashima, H. [2 ]
机构：
[1] Osaka Gen Med Ctr, Dept Pediat, Sumiyoshi Ku, Osaka 5588558, Japan
[2] Tokyo Med Univ, Dept Pediat, Tokyo, Japan
来源：
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2011年 / 30卷 / 01期
关键词：
NECROSIS-FACTOR-ALPHA;
D O I：
10.1007/s10096-010-1041-9
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We report the systemic cytokine and chemokine response in children with the 2009 pandemic influenza A (H1N1) virus infection. In patients with pneumonia, the serum levels of IFN-gamma and IL-5 were significantly higher than those in patients without pneumonia. This tendency was also present for IL-6, IL-8, IL-10, IL-13, and MCP-1 in patients with pneumonia. Among patients with pneumonia, the levels of MCP-1 were significantly higher in the group of patients with pneumonia with severe respiratory failure than patients with mild pneumonia.
引用
收藏
页码：117 / 120
页数：4
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