Hypoxia and Metastasis in Breast Cancer

被引:24
|
作者
Rundqvist, Helene [1 ]
Johnson, Randall S. [1 ]
机构
[1] Univ Calif San Diego, Mol Biol Sect, Div Biol Sci, La Jolla, CA 92093 USA
关键词
ENDOTHELIAL GROWTH-FACTOR; EPITHELIAL-MESENCHYMAL TRANSITION; UROKINASE RECEPTOR EXPRESSION; INDUCIBLE FACTOR HIF-1-ALPHA; INTERSTITIAL FLUID PRESSURE; AUTOCRINE MOTILITY FACTOR; TUMOR-SUPPRESSOR PROTEIN; LYMPH-NODE METASTASIS; CARBONIC-ANHYDRASE-IX; E-CADHERIN EXPRESSION;
D O I
10.1007/82_2010_77
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In this review we summarize the evidence for a role for hypoxic response in the biology of metastasis, with a particular emphasis on the metastasis of breast cancer and the function of the hypoxia inducible factor (HIF).
引用
收藏
页码:121 / 139
页数:19
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