Hypoxia and Metastasis in Breast Cancer

被引:24
|
作者
Rundqvist, Helene [1 ]
Johnson, Randall S. [1 ]
机构
[1] Univ Calif San Diego, Mol Biol Sect, Div Biol Sci, La Jolla, CA 92093 USA
关键词
ENDOTHELIAL GROWTH-FACTOR; EPITHELIAL-MESENCHYMAL TRANSITION; UROKINASE RECEPTOR EXPRESSION; INDUCIBLE FACTOR HIF-1-ALPHA; INTERSTITIAL FLUID PRESSURE; AUTOCRINE MOTILITY FACTOR; TUMOR-SUPPRESSOR PROTEIN; LYMPH-NODE METASTASIS; CARBONIC-ANHYDRASE-IX; E-CADHERIN EXPRESSION;
D O I
10.1007/82_2010_77
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In this review we summarize the evidence for a role for hypoxic response in the biology of metastasis, with a particular emphasis on the metastasis of breast cancer and the function of the hypoxia inducible factor (HIF).
引用
收藏
页码:121 / 139
页数:19
相关论文
共 50 条
  • [1] STROMAL HYPOXIA AND METASTASIS IN BREAST CANCER
    Rundqvist, H.
    Stockmann, C.
    Branco-Price, C.
    Doedens, A.
    Johnson, R. S.
    ANTICANCER RESEARCH, 2014, 34 (10) : 6145 - 6146
  • [2] Implications of Hypoxia in Breast Cancer Metastasis to Bone
    Gilkes, Daniele M.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 17 (10)
  • [3] RhoB is regulated by hypoxia and modulates metastasis in breast cancer
    Ju, Julia A.
    Godet, Ines
    DiGiacomo, Josh W.
    Gilkes, Daniele M.
    CANCER REPORTS, 2020, 3 (01)
  • [4] TGFBI modulates tumour hypoxia and promotes breast cancer metastasis
    Fico, Flavia
    Santamaria-Martinez, Albert
    MOLECULAR ONCOLOGY, 2020, 14 (12) : 3198 - 3210
  • [5] Role of hypoxia-inducible factors in breast cancer metastasis
    Gilkes, Daniele M.
    Semenza, Gregg L.
    FUTURE ONCOLOGY, 2013, 9 (11) : 1623 - 1636
  • [6] Hypoxia-inducible factor 1 and breast cancer metastasis
    Liu, Zhao-ji
    Semenza, Gregg L.
    Zhang, Hua-feng
    JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B, 2015, 16 (01): : 32 - 43
  • [7] Hypoxia and Cancer Metastasis Preface
    Gilkes, Daniele M.
    HYPOXIA AND CANCER METASTASIS, 2019, 1136 : V - V
  • [8] Interplay between desmoglein2 and hypoxia controls metastasis in breast cancer
    Chang, Po-Hao
    Chen, Min-Che
    Tsai, Ya-Ping
    Tan, Grace Y. T.
    Hsu, Pang-Hung
    Jeng, Yung-Ming
    Tsai, Yi-Fang
    Yang, Muh-Hwa
    Hwang-Verslues, Wendy W.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (03)
  • [9] Interaction between Desmoglein2 and hypoxia controls breast cancer metastasis
    Hwang-Verslues, Wendy W.
    Chang, Po-Hao
    CANCER RESEARCH, 2021, 81 (05)
  • [10] BACH1 regulates the hypoxia response and metastasis in triple negative breast cancer
    Nguyen, Long C.
    Dann, Christopher
    Yang, Dongbo
    Shi, Emily
    Li, Thomas
    Stock, Leticia
    Henn, Madeline
    Khramtsova, Galina
    Liu, Wenchao
    Matsumoto, Mitsuyo
    Olopade, Olufunmilayo
    Igarashi, Kazuhiko
    Rosner, Marsha
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2023, 32 (12)