A Novel Cell Irradiation System Using 90°-Scattering Technique

被引:3
|
作者
Cho, I. C. [1 ]
Weng, M. F. [2 ,3 ]
Wu, J. M. [4 ,5 ]
Chiang, S. Y. [2 ]
Chou, W. T. [1 ]
Niu, H. [6 ]
Hsu, C. H. [1 ]
机构
[1] Natl Tsing Hua Univ, Dept Biomed Engn & Environm Sci, Hsinchu 30013, Taiwan
[2] Natl Synchrotron Radiat Res Ctr, Hsinchu 30076, Taiwan
[3] Natl Chiao Tung Univ, Dept Appl Chem, Hsinchu 30010, Taiwan
[4] E Da Hosp, Dept Radiat Oncol, Yan Chau Shiang 82, Kaohsiung Cty, Taiwan
[5] I Shou Univ, Dept Med Imagines & Radiol Sci, Yan Chau Shiang 824, Kaohsiung Cty, Taiwan
[6] Natl Tsing Hua Univ, Nucl Sci & Technol Dev Ctr, Hsinchu 30013, Taiwan
关键词
Accelerator; biological effect of radiation; ion beam applications;
D O I
10.1109/TNS.2010.2087036
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
A novel cell irradiation system was developed for use with the HVEE Van de Graaff accelerator at the National Tsing Hua University. A 90 degrees-scattering technique using an Au foil was designed, in which charged particles were directed from horizontal to vertical irradiation. Beam performance was tested with a silicon detector and a CR-39 nuclear track detector. The HeLa cells were irradiated with 2-MeV alpha particles and the formation of giant cells was observed. The result showed that this system provides a convenient way of generating a vertical particle beam and a cell-supporting chamber, thereby allowing a suitable cell growth condition during irradiation. Furthermore, establishment of such a system is more convenient and economical than the alternatives.
引用
收藏
页码:95 / 98
页数:4
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