The Hepatic Stellate Cells (HSTCs) and Adipose-derived Mesenchymal Stem Cells (ASCs) Axis as a Potential Major Driver of Metabolic Syndrome - Novel Concept and Therapeutic Implications

被引：0

作者：

Marycz, Krzysztof ^{[1
,2
,3
]}

Kornicka-Garbowska, Katarzyna ^{[1
,2
]}

Galuppo, Larry ^{[3
]}

Bourebaba, Lynda ^{[1
]}

机构：

[1] Wroclaw Univ Environm & Life Sci, Fac Biol & Anim Sci, Dept Expt Biol, Norwida 27B, PL-50375 Wroclaw, Poland

[2] Int Inst Translat Med, Jesionowa 11,Malin 55-114, Wisznia Mala, Poland

[3] Univ Calif Davis, Sch Vet Med, Dept Surg & Radiol Sci, Davis, CA 95616 USA

来源：

STEM CELL REVIEWS AND REPORTS | 2022年 / 18卷 / 04期

关键词：

HSTCs; ASCs; A-Reg; Hepatokines; Adipokines; Metabolic syndrome; Crosstalk; OBESITY; DISEASE;

D O I：

10.1007/s12015-021-10304-w

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Herein, we would like to introduce a novel concept for the prevention and treatment of metabolic syndrome, which is based on molecular relationship between liver and adipose tissue. Particularly, we believe, that unravelling the molecular crosstalk between hepatokines and adipokines will allow to better understand the pathophysiology of metabolic diseases and allow to develop novel, effective therapeutic solutions against obesity and metabolic syndrome.

引用

页码：1417 / 1422

页数：6

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