NSAIDs and anastomotic leak: What's the evidence?

被引：1

作者：

Lee, Lawrence ^{[1
,2
]}

Fiore, Julio F., Jr. ^{[1
,2
]}

机构：

[1] McGill Univ, Dept Surg, Montreal, PQ, Canada

[2] McGill Univ, Steinberg Bernstein Ctr Minimally Invas Surg & In, Hlth Ctr, Montreal, PQ, Canada

来源：

SEMINARS IN COLON AND RECTAL SURGERY | 2021年 / 32卷 / 03期

关键词：

NSAIDs; Colorectal surgery; Anastomotic leak; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; ENHANCED RECOVERY; COLORECTAL SURGERY; AMERICAN-SOCIETY; NONOPIOID ANALGESICS; COLONIC ANASTOMOSES; POSTOPERATIVE PAIN; PLUS CODEINE; OPIOID USE; RISK;

D O I：

10.1016/j.scrs.2021.100833

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Non steroidal anti inflammatory drugs (NSAIDs) are effective analgesics and may be a valuable component of opioid-sparing perioperative analgesic strategies following colorectal surgery. However, NSAIDs may also impair wound healing and have been associated with an increased risk of anastomotic leak in some reports. In this chapter we will review the benefits of NSAIDs in managing postoperative pain, and review and critique the body of evidence on the association between NSAIDs and anastomotic leaks after colorectal surgery. (C) 2021 Elsevier Inc. All rights reserved.

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页数：6

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