X-ray repair cross-complementing group 3 common polymorphism is not associated with cervical cancer risk

被引：0

作者：

Cao, Yi ^{[1
]}

Chen, Wei ^{[1
]}

Xia, Yi ^{[2
]}

Zhao, Ge ^{[3
]}

Hu, Zheng ^{[1
]}

Xie, Xin-Hua ^{[1
]}

机构：

[1] Fudan Univ, Cent Hosp Minhang Dist, Minhang Hosp, Dept Obstet & Gynecol, 170 Xin Song Rd, Shanghai, Peoples R China

[2] Fudan Univ, Shanghai Canc Ctr, Minhang Branch, Dept Radiat Oncol, Shanghai, Peoples R China

[3] Xi An Jiao Tong Univ, Hosp 1, Dept Anesthesia, Xian, Shanxi, Peoples R China

来源：

BIOMEDICAL RESEARCH-INDIA | 2017年 / 28卷 / 17期

关键词：

Cervical cancer; X-ray repair cross-complementing group 3; Meta-analysis; Polymorphism; XRCC3; SUSCEPTIBILITY; CARCINOMA;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Recently, some reports investigated the association between X-ray Repair Cross-Complementing group 3 (XRCC3) and cervical cancer risk. However, the results were inconclusive. The meta-analysis, thus, assessed whether XRCC3 T241M polymorphism was associated with cervical cancer risk. Odds Ratios (ORs) with 95% Confidence Intervals (CIs) were calculated. Five case-control studies with a total of 806 cervical cancer cases and 850 controls were included. No association between XRCC3 T241M polymorphism and cervical cancer risk was found. In subgroup analysis, Asians with this polymorphism seemed to be associated with cervical cancer risk. Publication bias was not performed. In conclusion, this meta-analysis suggested that XRCC3 T241M polymorphism was not associated with cervical cancer risk.

引用

页码：7370 / 7372

页数：3

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