Coordination induced supramolecular assembly of fluorescent C-Phycocyanin for biologic discrimination of metal ions

被引:6
|
作者
Han, Xiangsheng [1 ,2 ]
Lv, Lili [1 ,2 ]
Yu, Daoyong [3 ]
Wu, Xiaochen [1 ]
Li, Chaoxu [1 ,2 ]
机构
[1] Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[3] China Univ Petr East China, Ctr Bioengn & Biotechnol, Qingdao 266580, Peoples R China
关键词
C-Phycocyanin; Metal ions; Coordination; Supramolecular assembly; Biologic probe; PROTEINS; PLATFORM; GRAPHENE;
D O I
10.1016/j.matlet.2017.12.116
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Living microbes can accumulate and exhibit distinct responses to different metal ions by strong coordination between bio-macromolecules and metal ions. Thus carefully selected bio-macromolecules could possibly serve as sensitive biologic probes to discriminate toxic metal ions. C-Phycocyanin (C-PC), a water-soluble phycobiliprotein widespread in algae, was selected as a unique biologic probe. Heavy-metal ions coordinated with C-PC, altered greatly secondary structures and fluorescence of C-PC, and also induced supramolecular fibrillation, in contrast to inert response of other metal ions. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:238 / 241
页数:4
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