Economic evaluation of prostate cancer screening: a systematic review

被引:8
|
作者
Lao, Chunhuan [1 ]
Brown, Charis [1 ]
Rouse, Paul [2 ]
Edlin, Richard [3 ]
Lawrenson, Ross [1 ]
机构
[1] Univ Auckland, Hamilton, New Zealand
[2] Univ Auckland, Sch Business, Auckland 1, New Zealand
[3] Univ Auckland, Sch Populat Hlth, Auckland 1, New Zealand
关键词
cost; cost-effectiveness threshold; economic evaluation; prostate cancer; quality of life; screening; ASYMPTOMATIC MEN; COST; ANTIGEN; MORTALITY; PROGRAM; OVERDETECTION; POPULATION; STRATEGIES; VALUES;
D O I
10.2217/fon.14.273
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This review, based on published papers, aims to describe the costs of prostate cancer screening and to examine whether prostate cancer screening is cost effective. The estimated cost per cancer detected ranged from Euro1299 in The Netherlands to US$44,355 in the USA. The estimated cost per life-year saved ranged from US$3000 to US$729,000, while the cost per quality-adjusted life year (QALY) was AU$291,817 and Can$371,100. The most appropriate data for economic evaluation of prostate cancer screening should be the cost per QALY gained. The estimated costs per QALY gained by prostate cancer screening were significantly higher than the cost-effectiveness threshold, suggesting that even when based on favorable randomized controlled trials in younger age groups, prostate cancer screening is still not cost effective.
引用
收藏
页码:467 / 477
页数:11
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