War on Viruses: LC3 Recruits GTPases

被引：1
|
作者：
Kuriakose, Teneema [1 ]
Kanneganti, Thirumala-Devi [1 ]
机构：
[1] St Jude Childrens Res Hosp, Dept Immunol, 332 N Lauderdale St, Memphis, TN 38105 USA
来源：
CELL HOST & MICROBE | 2017年 / 22卷 / 01期
关键词：
INDUCIBLE GTPASES; AUTOPHAGY; COMPLEX; SYSTEM;
D O I：
10.1016/j.chom.2017.06.019
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Interferon effector functions and autophagy are evolutionarily conserved arms of cell-autonomous immunity that restrict replication of intracellular pathogens. In this issue of Cell Host and Microbe, Biering et al., (2017) demonstrate how host cells co-opt sequential action of autophagy proteins and IFN-inducible GTPases to inhibit replication of positive-sense RNA viruses.
引用
收藏
页码：7 / 9
页数：4
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