Ni(II)-catalyzed conia-ene reaction of 1,3-dicarbonyl compounds with alkynes

被引：97

作者：

Gao, Q ^{[1
]}

Zheng, BF ^{[1
]}

Li, JH ^{[1
]}

Yang, D ^{[1
]}

机构：

[1] Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 11期

关键词：

D O I：

10.1021/ol050532q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have discovered a Ni(II)-catalyzed Conia-ene reaction of 1,3-dicarbonyl compounds with alkynes. In the presence of Ni(acac)(2) and Yb(OTf)(3), various acetylenic 1,3-dicarbonyl compounds underwent Conia-ene reaction to give mono- and bicyclic olefinic cyclopentanes. A mechanism involving the enol-yne-Ni complex formation is proposed and supported by deuterium-labeling experiments.

引用

页码：2185 / 2188

页数：4

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