ENHANCED EFFICACY OF IGF1R INHIBITION IN PEDIATRIC GLIOBLASTOMA BY COMBINATORIAL TARGETING OF PDGFRALPHA/BETA

被引:0
|
作者
Bielen, Aleksandra
Perryman, Lara
Box, Gary
Popov, Sergey
Jeay, Sebastein
Hofmann, Francesco
Hargrave, Darren
Eccles, Sue
Jones, Chris
机构
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:84 / 85
页数:2
相关论文
共 50 条
  • [21] IGF1R activation and the in vitro antiproliferative efficacy of IGF1R inhibitor are inversely correlated with IGFBP5 expression in bladder cancer
    Yann Neuzillet
    Elodie Chapeaublanc
    Clémentine Krucker
    Leanne De Koning
    Thierry Lebret
    François Radvanyi
    Isabelle Bernard-Pierrot
    BMC Cancer, 17
  • [22] IGF2 and IGF1R in pediatric adrenocortical tumors: roles in metastasis and steroidogenesis
    Peixoto Lira, Regia Caroline
    Fedatto, Paola Fernanda
    Marco Antonio, David Santos
    Leal, Leticia Ferro
    Martinelli, Carlos Eduardo
    de Castro, Margaret
    Tucci, Silvio
    Neder, Luciano
    Ramalho, Leandra
    Seidinger, Ana Luiza
    Cardinalli, Izilda
    Mastellaro, Maria Jose
    Yunes, Jose Andres
    Brandalise, Silvia Regina
    Tone, Luiz Gonzaga
    Rauber Antonini, Sonir Roberto
    Scrideli, Carlos Alberto
    ENDOCRINE-RELATED CANCER, 2016, 23 (06) : 481 - 493
  • [23] Targeting IGF1R pathway in cancer with microRNAs: How close are we?
    Kumar, Arathy S.
    Rayala, Suresh K.
    Venkatraman, Ganesh
    RNA BIOLOGY, 2018, 15 (03) : 320 - 326
  • [24] An innovative fluorescent probe targeting IGF1R for breast cancer diagnosis
    Xu, Haoran
    Zhao, Yue
    Gao, Xin
    Wang, Fang
    Gu, Yueqing
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 219
  • [25] Inhibition of the novel therapeutic target pregnancy associated plasma protein A (PAPP-A) in Ewing sarcoma enhances efficacy of IGF1R targeting in vivo
    Heitzeneder, Sabine
    Shern, John F.
    Helman, Lee J.
    Khan, Javed
    Mackall, Crystal L.
    CANCER RESEARCH, 2017, 77
  • [26] miR-422a Inhibits Glioma Proliferation and Invasion by Targeting IGF1 and IGF1R
    Wang, Haiyang
    Tang, Chongyang
    Na, Meng
    Ma, Wei
    Jiang, Zhenfeng
    Gu, Yifei
    Ma, Guizhen
    Ge, Haitao
    Shen, Hong
    Lin, Zhiguo
    ONCOLOGY RESEARCH, 2017, 25 (02) : 187 - 194
  • [27] Dual inhibition of RAS and the IGF2/IGF1R pathways: a potential targeting strategy for RAS-mutated embryonal rhabdomyosarcoma
    Sadeghian, Dorsay
    Lin, Wan-Hsin
    Smadbeck, James
    Panheiter, Alan
    Barrett, Michael
    Mccune, Alexa F.
    Karagouga, Giannoula
    Johnson, Sarah
    Feathers, Ryan W.
    Harris, Faye R.
    Kinsella, Lindsey
    Berry, Taylor
    Cheville, John
    Anastasiadis, Panos
    Granberg, Candace
    Gargollo, Patricio
    George, Vasmatzis
    CANCER RESEARCH, 2023, 83 (07)
  • [28] IGF1R inhibition effect on TTFields treated epithelial ovarian cancer
    Haber, Lior Gal
    Sharon, Shilhav Meisel
    Hallak, Mordechai
    Werner, Haim
    Bruchim, Ilan
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2024, 34 (SUPPL_1) : A387 - A387
  • [29] Activation Versus Inhibition of IGF1R: A Dual Role in Breast Tumorigenesis
    Bulatowicz, Joseph J.
    Wood, Teresa L.
    FRONTIERS IN ENDOCRINOLOGY, 2022, 13
  • [30] IGF1R and Src inhibition induce synergistic cytotoxicity in HNSCC through inhibition of FAK
    Christine E. Lehman
    Adam Spencer
    Sarah Hall
    Jeremy J. P. Shaw
    Julia Wulfkuhle
    Emanuel F. Petricoin
    Stefan Bekiranov
    Mark J. Jameson
    Daniel Gioeli
    Scientific Reports, 11