Ananas comosus Effect on Perineal Pain and Wound Healing After Episiotomy: A Randomized Double-Blind Placebo-Controlled Clinical Trial

被引:32
|
作者
Golezar, Samira [1 ,2 ]
机构
[1] Shahid Beheshti Univ Med Sci, Sch Nursing & Midwifery, Student Res Comm, Tehran, Iran
[2] Islamic Azad Univ, Toyserkan Branch, Dept Midwifery, Toyserkan, Iran
关键词
Bromelains; Pain; Episiotomy; Wound Healing; BROMELAIN; EFFICACY; THERAPY;
D O I
10.5812/ircmj.21019
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Ananas comosus has long been used for medical purposes. Currently, we are experiencing an unprecedented interest in the use of complementary medicine as well as a growing attention to traditional products such as bromelain for wound healing and reducing pain. Objectives: The aim of this study was to determine the effect of oral bromelain on perineal pain and wound healing after episiotomy in primiparous women. Patients and Methods: In this double-blind placebo-controlled clinical trial, 82 primiparous women fulfilling the inclusion criteria received bromelain or placebo randomly Participants were given three tablets, three times a day for six successive days. The initial dose was given 2 hours after delivery. Episiotomy pain was measured using VAS scale before the initial dose, as well as on theist hour and on the 3rd, 7th and 14th days after the initial dose. Wound healing was measured using REEDA scale on the 3rd, 7th and 14th days after delivery Results: Episiotomy pain significantly reduced in bromelain group compared with the placebo group (P < 0.05) and wound healing was faster in bromelain group compared with the placebo group (P < 0.05) on follow-up days. Conclusions: The results showed the effectiveness of bromelain on episiotomy pain and wound healing. Therefore, it is suggested to use bromelain in postoperative stage to improve wound healing and reduce pain.
引用
收藏
页数:6
相关论文
共 50 条
  • [41] Intrathecal ziconotide in the treatment of chronic nonmalignant pain: A randomized, double-blind, placebo-controlled clinical trial
    Wallace, MS
    Charapata, SG
    Fisher, R
    Byas-Smith, M
    Staats, PS
    Mayo, M
    McGuire, D
    Ellis, D
    NEUROMODULATION, 2006, 9 (02): : 75 - 86
  • [42] Effect of sulpiride on menopausal hot flashes: a randomized, double-blind, placebo-controlled clinical trial
    Moreira Borba, Clarissa
    Francisco Ferreira, Charles
    Vargas Ferreira, Fernanda
    Perez-Lopez, Faustino R.
    Osorio Wender, Maria Celeste
    GYNECOLOGICAL ENDOCRINOLOGY, 2020, 36 (03) : 247 - 251
  • [43] The effect of symbiotic in the treatment of infantile colic: A double-blind, randomized, placebo-controlled clinical trial
    Khoshnevisasl, Parisa
    Sadeghzadeh, Mansour
    Kamali, Koorosh
    Hasanlo, Masoumeh
    JOURNAL OF RESEARCH IN MEDICAL SCIENCES, 2022, 27 (01): : 42
  • [44] Therapeutic effect of Achillea millefolium on the hemorrhoids; A randomized double-blind placebo-controlled clinical trial
    Mahmoudi, Aynaz
    Seyedsadeghi, Mirsalim
    Miran, Mansour
    Ahari, Saeid Sadeghieh
    Layegh, Hojat
    Mostafalou, Sara
    JOURNAL OF HERBAL MEDICINE, 2023, 39
  • [45] Metformin effect on TSH in subclinical hypothyroidism: randomized, double-blind, placebo-controlled clinical trial
    Mateus Dornelles Severo
    Thais Stürmer Andrade
    Vicente Correa Junior
    Alexandre Antonio Naujorks
    Miguel Gus
    Beatriz D. Schaan
    Endocrine, 2018, 59 : 66 - 71
  • [46] The effect of silk peptide on immune system, A randomized, double-blind, placebo-controlled clinical trial
    Hwang, Jin-Taek
    Cho, Jung Min
    Jeong, In Hye
    Lee, Jeong-yong
    Ha, Ki-Chan
    Baek, Hyang-Im
    Yang, Hye Jeong
    Kim, Min Jung
    Lee, Jong Ho
    JOURNAL OF FUNCTIONAL FOODS, 2019, 55 : 275 - 284
  • [47] Metformin effect on TSH in subclinical hypothyroidism: randomized, double-blind, placebo-controlled clinical trial
    Severo, Mateus Dornelles
    Andrade, Thais Sturmer
    Correa Junior, Vicente
    Naujorks, Alexandre Antonio
    Gus, Miguel
    Schaan, Beatriz D.
    ENDOCRINE, 2018, 59 (01) : 66 - 71
  • [48] Gabapentin for Postoperative Pain After Photorefractive Keratectomy: A Prospective, Randomized, Double-blind, Placebo-controlled Trial
    Lichtinger, Alejandro
    Purcell, Tracy L.
    Schanzlin, David J.
    Chayet, Arturo S.
    JOURNAL OF REFRACTIVE SURGERY, 2011, 27 (08) : 613 - 617
  • [49] Effect of Minocycline on Lumbar Radicular Neuropathic Pain A Randomized, Placebo-controlled, Double-blind Clinical Trial with Amitriptyline as a Comparator
    Vanelderen, Pascal
    Van Zundert, Jan
    Kozicz, Tamas
    Puylaert, Martine
    De Vooght, Pieter
    Mestrum, Roel
    Heylen, Rene
    Roubos, Eric
    Vissers, Kris
    ANESTHESIOLOGY, 2015, 122 (02) : 399 - 406
  • [50] Tramadol in Neuropathic Pain After Spinal Cord Injury A Randomized, Double-blind, Placebo-controlled Trial
    Norrbrink, Cecilia
    Lundeberg, Thomas
    CLINICAL JOURNAL OF PAIN, 2009, 25 (03): : 177 - 184