IRF8 represses GM-CSF expression in tumor cells to mediate myeloid-derived suppressor cell differentiation.

被引：0
|
作者：
Paschall, Amy V. [1 ,2 ]
Redd, Priscilla [1 ,2 ]
Zhang, Ruihua [3 ]
Xiong, Huabao [3 ]
Abrams, Scott I. [4 ]
Liu, Kebin [1 ,2 ]
机构：
[1] Georgia Regents Univ, Augusta, GA USA
[2] Charlie Norwood VA Med Ctr, Augusta, GA USA
[3] Icahn Sch Med Mt Sinai, New York, NY 10029 USA
[4] Roswell Pk Canc Inst, Buffalo, NY 14263 USA
来源：
JOURNAL OF IMMUNOLOGY | 2016年 / 196卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
211.10
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Negative impact of myeloid-derived suppressor cells on CD8 effector T cell trafficking within the tumor microenvironment
    Ku, Amy
    Muhitch, Jason
    Abrams, Scott
    Evans, Sharon
    JOURNAL OF IMMUNOLOGY, 2014, 192
  • [42] Alleviation of skin inflammation after Lin− cell transplantation correlates with their differentiation into myeloid-derived suppressor cells
    Su Jeong Ryu
    Ji-Min Ju
    Woojin Kim
    Min Bum Kim
    Kuen Hee Oh
    Dong Sup Lee
    Hakmo Lee
    Ju Eun Oh
    Kyong Soo Park
    Eun Young Choi
    Scientific Reports, 5
  • [43] The expression profiles and regulation of PD-Li in tumor-induced myeloid-derived suppressor cells
    Lu, Chunwan
    Savage, Natasha
    Singh, Nagendra
    Liu, Kebin
    JOURNAL OF IMMUNOLOGY, 2017, 198 (01):
  • [44] Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis
    Ibrahim, Mohammed L.
    Klement, John D.
    Lu, Chunwan
    Redd, Priscilla S.
    Xiao, Wei
    Yang, Dafeng
    Browning, Darren D.
    Savage, Natasha M.
    Buckhaults, Phillip J.
    Morse, Herbert C., III
    Liu, Kebin
    CELL REPORTS, 2018, 25 (11): : 3036 - +
  • [45] Monocytic myeloid-derived suppressor cells as a potent suppressor of tumor immunity in non-small cell lung cancer
    Pogoda, Katarzyna
    Pyszniak, Maria
    Rybojad, Pawel
    Tabarkiewicz, Jacek
    ONCOLOGY LETTERS, 2016, 12 (06) : 4785 - 4794
  • [46] Anti-VEGF therapy resistance in ovarian cancer is caused by GM-CSF-induced myeloid-derived suppressor cell recruitment
    Horikawa, Naoki
    Abiko, Kaoru
    Matsumura, Noriomi
    Baba, Tsukasa
    Hamanishi, Junzo
    Yamaguchi, Ken
    Murakami, Ryusuke
    Taki, Mana
    Ukita, Masayo
    Hosoe, Yuko
    Koshiyama, Masafumi
    Konishi, Ikuo
    Mandai, Masaki
    BRITISH JOURNAL OF CANCER, 2020, 122 (06) : 778 - 788
  • [47] The effects of dendritic cell-based vaccines in the tumor microenvironment: Impact on myeloid-derived suppressor cells
    Luisa Sanchez-Leon, Maria
    Jimenez-Cortegana, Carlos
    Cabrera, Gabriel
    Monica Vermeulen, Elba
    de la Cruz-Merino, Luis
    Sanchez-Margalet, Victor
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [48] Anti-VEGF therapy resistance in ovarian cancer is caused by GM-CSF-induced myeloid-derived suppressor cell recruitment
    Naoki Horikawa
    Kaoru Abiko
    Noriomi Matsumura
    Tsukasa Baba
    Junzo Hamanishi
    Ken Yamaguchi
    Ryusuke Murakami
    Mana Taki
    Masayo Ukita
    Yuko Hosoe
    Masafumi Koshiyama
    Ikuo Konishi
    Masaki Mandai
    British Journal of Cancer, 2020, 122 : 778 - 788
  • [49] Circulating and Tumor Myeloid-derived Suppressor Cells in Resectable Non-Small Cell Lung Cancer
    Yamauchi, Yoshikane
    Safi, Seyer
    Blattner, Carolin
    Rathinasamy, Anchana
    Umansky, Ludmila
    Juenger, Simone
    Warth, Arne
    Eichhorn, Martin
    Muley, Thomas
    Herth, Felix J. F.
    Dienemann, Hendrik
    Platten, Michael
    Beckhove, Philipp
    Utikal, Jochen
    Hoffmann, Hans
    Umansky, Viktor
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2018, 198 (06) : 777 - 787
  • [50] Implication of STAT-5 Recruitment in the Expression of IRF-8 and in the Impairment of Human Plasmacytoid Dendritic Cells Differentiation Induced by BCR-ABL and GM-CSF
    Barra, Anne
    Brault, Lucie
    Turhan, Ali G.
    Roy, Lydia
    Guilhot, Frangois
    Gombert, Jean-Marc
    BLOOD, 2008, 112 (11) : 1097 - 1097
12345