IRF8 represses GM-CSF expression in tumor cells to mediate myeloid-derived suppressor cell differentiation.

被引:0
|
作者
Paschall, Amy V. [1 ,2 ]
Redd, Priscilla [1 ,2 ]
Zhang, Ruihua [3 ]
Xiong, Huabao [3 ]
Abrams, Scott I. [4 ]
Liu, Kebin [1 ,2 ]
机构
[1] Georgia Regents Univ, Augusta, GA USA
[2] Charlie Norwood VA Med Ctr, Augusta, GA USA
[3] Icahn Sch Med Mt Sinai, New York, NY 10029 USA
[4] Roswell Pk Canc Inst, Buffalo, NY 14263 USA
来源
JOURNAL OF IMMUNOLOGY | 2016年 / 196卷
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
211.10
引用
收藏
页数:2
相关论文
共 50 条
  • [1] IRF8 regulates GM-CSF expression in T cells and tumor cells to mediate myeloid-derived suppressor cell differentiation
    Paschall, Amy
    Zhang, Ruihua
    Bardhan, Kankana
    Qi, Chen-Feng
    Peng, Liang
    Lu, Geming
    Yang, Jianjun
    Merad, Miriam
    Zimmerman, Mary
    McGaha, Tracy
    Zhou, Gang
    Mellor, Andrew
    Abrams, Scott I.
    Morse, Herbert
    Ozato, Keiko
    Xiong, Huabao
    Liu, Kebin
    CANCER IMMUNOLOGY RESEARCH, 2015, 3 (10)
  • [2] IRF8 expressed in T cells regulates GM-CSF expression to control myeloid derived suppressor cell differentiation
    Paschall, Amy
    Zhang, Rui-hua
    Qi, Chen-Feng
    Bardhan, Kankana
    Peng, Liang
    Lu, Geming
    Yang, Jianjun
    Merad, Miriam
    McGaha, Tracy
    Zhou, Gang
    Mellor, Andrew
    Abrams, Scott
    Morse, Herbert
    Ozato, Keiko
    Xiong, Huabao
    Liu, Kebin
    JOURNAL OF IMMUNOLOGY, 2015, 194
  • [3] IRF8 deficiency in colonic epithelial cells promotes inflammation-mediated colon tumorigenesis and myeloid-derived suppressor cell differentiation.
    Ibrahim, Mohammed L.
    Liu, Kebin
    JOURNAL OF IMMUNOLOGY, 2017, 198 (01):
  • [4] IFN Regulatory Factor 8 Represses GM-CSF Expression in T Cells To Affect Myeloid Cell Lineage Differentiation
    Paschall, Amy V.
    Zhang, Ruihua
    Qi, Chen-Feng
    Bardhan, Kankana
    Peng, Liang
    Lu, Geming
    Yang, Jianjun
    Merad, Miriam
    McGaha, Tracy
    Zhou, Gang
    Mellor, Andrew
    Abrams, Scott I.
    Morse, Herbert C., III
    Ozato, Keiko
    Xiong, Huabao
    Liu, Kebin
    JOURNAL OF IMMUNOLOGY, 2015, 194 (05): : 2369 - 2379
  • [5] Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF
    Dolcetti, Luigi
    Peranzoni, Elisa
    Ugel, Stefano
    Marigo, Ilaria
    Fernandez Gomez, Audry
    Mesa, Circe
    Geilich, Markus
    Winkels, Gregor
    Traggiai, Elisabetta
    Casati, Anna
    Grassi, Fabio
    Bronte, Vincenzo
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2010, 40 (01) : 22 - 35
  • [6] FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape
    Wu, Lei
    Xu, Yanquan
    Zhao, Huakan
    Zhou, Yu
    Chen, Yu
    Yang, Shuai
    Lei, Juan
    Zhang, Jiangang
    Wang, Jingchun
    Wu, Yongzhong
    Li, Yongsheng
    THERANOSTICS, 2022, 12 (02): : 842 - 858
  • [7] IRF8 deficiency-induced myeloid-derived suppressor cell promote immune evasion in lung adenocarcinoma
    Gao, Zhen
    Liu, Shang
    Xiao, Han
    Li, Meng
    Ren, Wan-gang
    Xu, Lin
    Peng, Zhong-min
    JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 22 (01)
  • [8] SETD1B compensates loss of IRF8 expression to activate iNTOS expression in myeloid-derived suppressor cells through an epigenetic mechanism
    Redd, Priscilla S.
    Ibrahim, Mohammed L.
    Klement, John D.
    Sharman, Sarah K.
    Paschall, Amy V.
    Yang, Dafeng
    Nayak-Kapoor, Asha
    Liu, Kebin
    JOURNAL OF IMMUNOLOGY, 2017, 198 (01):
  • [9] Pegylated Murine GM-CSF Increases Myeloid Derived Suppressor Cells In Vivo
    Schroeder, Mark A.
    Ritchey, Julie
    Dieckgraefe, Brian K.
    DiPersio, John F.
    BLOOD, 2011, 118 (21) : 1280 - 1280
  • [10] Proliferation-independent GM-CSF and M-CSF signals control monocyte conversion into monocytic myeloid-derived suppressor cells
    Ribechini, E.
    Hutchinson, J. A.
    Hergovits, S.
    Heuer, M.
    Lucas, J.
    Schleicher, U.
    Garrote, A. L. Jordan
    Potter, S. J.
    Riquelme, P.
    Brackmann, H.
    Mueller, N.
    Raifer, H.
    Berberich, I.
    Huber, M.
    Beilhack, A.
    Lohoff, M.
    Bogdan, C.
    Eyrich, M.
    Hermanns, H. M.
    Geissler, E. K.
    Lutz, M.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2017, 47 : 248 - 248