Clinical management of Clostridium difficile -: Associated disease

被引:34
|
作者
Miller, Mark A. [1 ]
机构
[1] McGill Univ, Jewish Gen Hosp, Infect Prevent & Control, Div Infect Dis & Clin Microbiol, Montreal, PQ H3T 1E2, Canada
关键词
D O I
10.1086/519257
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The incidence of Clostridium difficile-associated disease (CDAD) and its serious complications ( including colectomy and death) have been increasing worldwide. This phenomenon is strongly associated with the appearance of a new "hypervirulent" strain in several countries. More-effective strategies are needed for the prevention and treatment of this entity. This article will review the current approaches using antimicrobials, probiotics, immunomodulation, surgery, and miscellaneous adjuvants to prevent and treat this infection.
引用
收藏
页码:S122 / S128
页数:7
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