Bioconjugated Quantum Dots as Fluorescent Probes for Biomedical Imaging

被引：33
|
作者：
Li, Zong-Huan [1 ]
Peng, Jun [2 ]
Chen, Hong-Lei [1 ]
机构：
[1] Wuhan Univ, Dept Pathol, Sch Basic Med Sci, Wuhan 430071, Peoples R China
[2] Wuhan Tumor Nanometer Diag Engn Res Ctr, Wuhan 430072, Peoples R China
来源：
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2011年 / 11卷 / 09期
基金：
中国国家自然科学基金;
关键词：
Quantum Dots; Molecular Detection; Cell Imaging; In Vivo Imaging; Nanotoxicity; RESONANCE ENERGY-TRANSFER; LIVE CELLS; SEMICONDUCTOR NANOCRYSTALS; CELLULAR UPTAKE; LIVING CELLS; REAL-TIME; TRACKING; PROTEIN; NANOPARTICLES; CANCER;
D O I：
10.1166/jnn.2011.5122
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Luminescent semiconductor quantum dots have become an important class of fluorescent labels for biological and biomedical imaging. In comparison with conventional organic dyes and fluorescent proteins, quantum dots have extraordinary fluorescent properties including high brightness, high resistance to photobleaching and tunable wavelengths. In this review, we briefly discuss the properties and modification of quantum dots. We focus on the applications of quantum dots in biomedical imaging, including molecular detection, live cell imaging and in vivo imaging. The toxicity of the quantum dots to cells and animals is also discussed.
引用
收藏
页码：7521 / 7536
页数：16
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