Copper(II) fluoride-catalyzed N-arylation of heterocycles with halothiophenes

被引：4
|
作者：
Arsenyan, Pavel [1 ]
Paegle, Edgars [1 ]
Petrenko, Alla [1 ]
Belyakov, Sergey [1 ]
机构：
[1] Latvian Inst Organ Synth, LV-1006 Riga, Latvia
来源：
TETRAHEDRON LETTERS | 2010年 / 51卷 / 38期
关键词：
Arylation; Bithiophene; Pyrazole; Thiophene; X-ray crystal structure; DERIVATIVES; IMIDAZOLES; PYRAZOLES;
D O I：
10.1016/j.tetlet.2010.07.094
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel, cheap copper(II) fluoride-mediated N-arylation of heterocycles with halothiophenes is described. The yield of the pyrazolylthiophene strongly depends on the nature of the initial thiophene. The molecular structure of 3,5-dimethyl-1-(5'-methyl-[2,2']bithienyl-5-yl)-1H-pyrazole was studied by X-ray diffraction. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5052 / 5055
页数：4
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