Granulocyte and monocyte apheresis therapy for patients with active ulcerative colitis associated with COVID-19

被引：3

作者：

Koroku, Miki ^{[1
]}

Omori, Teppei ^{[1
]}

Kambayashi, Harutaka ^{[1
]}

Murasugi, Shun ^{[1
]}

Kuriyama, Tomoko ^{[1
]}

Ikarashi, Yuichi ^{[1
]}

Yonezawa, Maria ^{[1
]}

Arimura, Ken ^{[2
]}

Karasawa, Kazunori ^{[3
]}

Hanafusa, Norio ^{[4
]}

Kawana, Masatoshi ^{[5
]}

Tokushige, Katsutoshi ^{[1
]}

机构：

[1] Tokyo Womens Med Univ, Inst Gastroenterol, Tokyo, Japan

[2] Tokyo Womens Med Univ, Dept Resp Med, Tokyo, Japan

[3] Tokyo Womens Med Univ, Dept Med, Div Nephrol, Tokyo, Japan

[4] Tokyo Womens Med Univ, Dept Blood Purificat, Tokyo, Japan

[5] Tokyo Womens Med Univ, Primary Care Ctr, Tokyo, Japan

来源：

INTESTINAL RESEARCH | 2022年 / 20卷 / 01期

关键词：

COVID-19; Granulocyte and monocyte adsorptive apheresis; Ulcerative colitis; ADSORPTION APHERESIS; MANAGEMENT;

D O I：

10.5217/ir.2020.00148

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARSCoV-2), is now a pandemic. Although several treatment guidelines have been proposed for patients who have both inflammatory bowel disease and COVID-19, immunosuppressive therapy is essentially not recommended, and the treatment options are limited. Even in the COVID-19 pandemic, adjuvant adsorptive granulocyte and monocyte apheresis may safely bring ulcerative colitis (UC) into remission by removing activated myeloid cells without the use of immunosuppressive therapy. Our patient was a 25-year-old Japanese male with UC and COVID-19. This is the first case report of the induction of UC remission with granulocyte and monocyte apheresis treatment for active UC associated with COVID-19. (Intest Res, Published online )

引用

页码：150 / 155

页数：6

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