Human stem cell-derived cardiomyocytes for pharmacological and toxicological modeling

被引:3
|
作者
Harding, Sian E. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, London SW7 2AZ, England
关键词
stem cell; in vitro; cardiomyocyte; high throughput;
D O I
10.1111/j.1749-6632.2011.06328.x
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Cardiomyocytes derived from human pluripotent stem cells have advantages for modeling in terms of phenotype, longevity in culture, ease of transfection, and high-throughput capability.
引用
收藏
页码:48 / 49
页数:2
相关论文
共 50 条
  • [31] Integrated analysis of human induced pluripotent stem cell-derived cardiomyocytes in diversity and disease modeling
    Majewski, David
    Liu, Jing
    Lor, Souameng
    Salvagiotto, Giorgia
    Hilcove, Simon
    Jones, Eugenia
    JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2020, 105
  • [32] Modeling trastuzumab-related cardiotoxicity in vitro using human stem cell-derived cardiomyocytes
    Kurokawa, Yosuke K.
    Shang, Michael R.
    Yin, Rose T.
    George, Steven C.
    TOXICOLOGY LETTERS, 2018, 285 : 74 - 80
  • [33] Modeling Cadmium-induced Cardiotoxicity Using Human Pluripotent Stem Cell-derived Cardiomyocytes
    Shen, Jiaxi
    Wang, Xiaochen
    Zhou, Danni
    Li, Tongyu
    Tang, Ling
    Gong, Tingyu
    Su, Jun
    Liang, Ping
    CIRCULATION RESEARCH, 2018, 123
  • [34] Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
    Rhee, June-Wha
    Yi, Hyoju
    Thomas, Dilip
    Lam, Chi Keung
    Belbachir, Nadjet
    Tian, Lei
    Qin, Xulei
    Malisa, Jessica
    Lau, Edward
    Paik, David T.
    Kim, Youngkyun
    Choi, Beatrice SeungHye
    Sayed, Nazish
    Sallam, Karim
    Liao, Ronglih
    Wu, Joseph C.
    CELL REPORTS, 2020, 32 (02):
  • [35] Modeling Diabetic Cardiomyopathy Model Using Human Induced Pluripotent Stem Cell-derived Cardiomyocytes
    Horikoshi, Yuichi
    Williams, Anna
    Bai, Xiaowen
    Yan, Yasheng
    Kwok, Wai-Meng
    Bosnjak, Zeliko
    CIRCULATION RESEARCH, 2016, 119
  • [36] Modeling Carfilzomib Induced Cardiotoxicity Using Human Induced Pluripotent Stem Cell-derived Cardiomyocytes
    Forghani, Parvin
    Rashid, Aysha
    Li, Dong
    Mandawat, Anant
    Xu, Chunhui
    CIRCULATION RESEARCH, 2020, 127
  • [37] Cell surface markers for immunophenotyping human pluripotent stem cell-derived cardiomyocytes
    Kenneth R. Boheler
    Ellen Ngar-Yun Poon
    Pflügers Archiv - European Journal of Physiology, 2021, 473 : 1023 - 1039
  • [38] The human embryonic stem cell-derived cardiomyocyte as a pharmacological model
    Harding, Sian E.
    Ali, Nadire N.
    Brito-Martins, Marta
    Gorelik, Julia
    PHARMACOLOGY & THERAPEUTICS, 2007, 113 (02) : 341 - 353
  • [39] Effect of Cell Labeling on the Function of Human Pluripotent Stem Cell-Derived Cardiomyocytes
    Choi, Seong Woo
    Cho, Young-Woo
    Kim, Jae Gon
    Kim, Yong-Jin
    Kim, Eunmi
    Chung, Hyung-Min
    Kang, Sun-Woong
    INTERNATIONAL JOURNAL OF STEM CELLS, 2020, 13 (02) : 287 - 294
  • [40] Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes
    Lopez, Colleen A.
    Al-Siddiqi, Heba Hussain A. A.
    Purnama, Ujang
    Iftekhar, Sonia
    Bruyneel, Arne A. N.
    Kerr, Matthew
    Nazir, Rabia
    Sousa Fialho, Maria da Luz
    Malandraki-Miller, Sophia
    Alonaizan, Rita
    Kermani, Fatemeh
    Heather, Lisa C.
    Czernuszka, Jan
    Carr, Carolyn A.
    SCIENTIFIC REPORTS, 2021, 11 (01)