CKD-581, a novel histone deacetylase inhibitor, synergistically enhances Bortezomib cytotoxicity in multiple myeloma cells

被引：1
|
作者：
Lee, Chansu [1 ]
Ahn, Kwang-Sung [2 ]
Jung, Woo June [1 ]
Koh, Youngil [2 ]
Kim, Hyo Jung [3 ]
Lee, Hyun Jung [4 ]
Yoon, Hwi-Joong [5 ]
Yoon, Sung-Soo [6 ]
机构：
[1] Seoul Natl Univ, Coll Med, Seoul, South Korea
[2] Seoul Natl Univ Hosp, Seoul 110744, South Korea
[3] Hallym Univ, Coll Med, Med Ctr, Seoul, South Korea
[4] Dongguk Univ, Ilsan Med Ctr, Seoul, South Korea
[5] Kyung Hee Univ, Sch Med, Med Ctr, Seoul, South Korea
[6] Seoul Natl Univ, Coll Med, Seoul Natl Univ Hosp, Seoul, South Korea
来源：
CANCER RESEARCH | 2014年 / 74卷 / 19期
关键词：
D O I：
10.1158/1538-7445.AM2014-1695
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1695
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Dual targeting of cell cycle checkpoint and histone deacetylase overcomes bortezomib resistance in multiple myeloma
    Tabayashi, Takayuki
    Tanaka, Yuka
    Takahashi, Yasuyuki
    Kimura, Yuta
    Tomikawa, Tatsuki
    Anan, Tomoe
    Sagawa, Morihiko
    Watanabe, Reiko
    Tokuhira, Michihide
    Kizaki, Masahiro
    CANCER RESEARCH, 2018, 78 (13)
  • [42] A histone deacetylase inhibitor enhances adenoviral infection of renal cancer cells
    Okegawa, Takatsugu
    Sayne, Jennifer R.
    Nutahara, Kikuo
    Pong, Rey-Chen
    Saboorian, Hossain
    Kabbani, Wareef
    Higashihara, Eiji
    Hsieh, Jer-Tsong
    JOURNAL OF UROLOGY, 2007, 177 (03): : 1148 - 1156
  • [43] Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways
    Doudican, Nicole A.
    Wen, Shih Ya
    Mazumder, Amitabha
    Orlow, Seth J.
    ONCOLOGY REPORTS, 2012, 28 (05) : 1851 - 1858
  • [44] Phase Ib dose escalation study of oral quisinostat, a histone deacetylase inhibitor, in combination with bortezomib and dexamethasone for patients with relapsed multiple myeloma
    Leleu, Xavier
    Touzeau, Cyrille
    Benboubker, Lotfi
    Facon, Thierry
    Delain, Martine
    Fourneau, Nele
    Phelps, Charles
    Forslund, Ann
    Hellemans, Peter
    Smit, Johan
    Badamo-Dotzis, Julie
    Moreau, Philippe
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [45] Gamma-secretase inhibitor enhances the cytotoxic effect of bortezomib in multiple myeloma
    Feng Chen
    Alexandra Pisklakova
    Ming Li
    Rachid Baz
    Daniel M. Sullivan
    Yulia Nefedova
    Cellular Oncology, 2011, 34 : 545 - 551
  • [46] Metformin Synergistically Enhances Antitumor Activity of Histone Deacetylase Inhibitor Trichostatin A Against Osteosarcoma Cell Line
    Duo, Jian
    Ma, Yulin
    Wang, Guowen
    Han, Xiuxin
    Zhang, Chao
    DNA AND CELL BIOLOGY, 2013, 32 (04) : 156 - 164
  • [47] Gamma-secretase inhibitor enhances the cytotoxic effect of bortezomib in multiple myeloma
    Chen, Feng
    Pisklakova, Alexandra
    Li, Ming
    Baz, Rachid
    Sullivan, Daniel M.
    Nefedova, Yulia
    CELLULAR ONCOLOGY, 2011, 34 (06) : 545 - 551
  • [48] NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma
    Catley, L
    Weisberg, E
    Tai, YT
    Atadja, P
    Remiszewski, S
    Hideshima, T
    Mitsiades, N
    Shringarpure, R
    LeBlanc, R
    Chauhan, D
    Munshi, NC
    Schlossman, R
    Richardson, P
    Griffin, J
    Anderson, KC
    BLOOD, 2003, 102 (07) : 2615 - 2622
  • [49] Effects of a novel histone deacetylase inhibitor, PXD101, when used as monotherapy or in combination with bortezomib on tumor growth in mouse models of human multiple myeloma.
    Campbell, Richard A.
    Sanchez, Eric
    Chen, Haiming
    Turker, Lauren
    Trac, Olivia
    Li, Mingjie
    Shalitin, Dror
    Gordon, Melinda S.
    Pang, Shen
    Bonavida, Benjamin
    Said, Jonathan
    Jeffers, Michael
    Qian, Xiaozhong
    Lichenstein, Henri S.
    Berenson, James R.
    BLOOD, 2006, 108 (11) : 993A - 993A
  • [50] Expression of histone deacetylase (HDAC) family members in bortezomib-refractory multiple myeloma and modulation by panobinostat
    Cheng, Tiewei
    Kiser, Kendall
    Grasse, Leslie
    Iles, Lakesla
    Bartholomeusz, Geoffrey
    Samaniego, Felipe
    Orlowski, Robert Z.
    Chandra, Joya
    CANCER DRUG RESISTANCE, 2021, 4 (04) : 888 - 902
12345