Sulfur-containing derivatives of 1,4-naphthoquinone, Part 1: Disulfide synthesis

被引:14
|
作者
Stasevych, MV [1 ]
Plotnikov, MY [1 ]
Platonov, MO [1 ]
Sabat, SI [1 ]
Musyanovych, RY [1 ]
Novikov, VP [1 ]
机构
[1] Natl Univ Lviv Polytech, Inst Chem & Chem Technol, Dept Technol Biol Act Subst Pharm & Biotechnol, UA-79013 Lvov, Ukraine
关键词
D O I
10.1002/hc.20112
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Disulfides of 1,4-naphthoquinone were synthesized, and different methods of their synthesis were investigated. High yields and purity of disulfides were obtained from the oxidation of thiol derivatives. The latter were prepared in high yields and purity from isothiuronic salts. The obtained disulfides are synthones for compounds with a wide spectrum of biological activity. (c) 2005 Wiley Periodicals, Inc.
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页码:205 / 211
页数:7
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