Randomised, double-blind, placebo-controlled study to assess long-term effect of dupilumab on prevention of lung function decline (LFD) in patients with uncontrolled moderate-to-severe asthma: ATLAS trial

被引:0
|
作者
Gomez, L. De Prado [1 ]
Pavord, I. [2 ]
Busse, W. [3 ]
Brightling, C. E. [4 ]
Wechsler, M. E. [5 ]
Rabe, K. F. [6 ,7 ,8 ]
Zhang, M. [9 ]
Xing, J. [9 ]
Jacob-Nara, J. A. [9 ]
Rowe, P. J. [9 ]
机构
[1] Sanofi, Reading, Berks, England
[2] Univ Oxford, NIHR Oxford Biomed Res Ctr, Oxford, England
[3] Univ Wisconsin, UW Allergy Pulm & Crit Care Med, Sch Med & Publ Hlth, Madison, WI USA
[4] Univ Leicester, Inst Lung Hlth, Dept Resp Sci, NIHR Leicester Biomed Res Ctr, Leicester, Leics, England
[5] Natl Jewish Hlth, Denver, CO USA
[6] LungenClin Grosshansdorf, Grosshansdorf, Germany
[7] German Ctr Lung Res DZL, ARCN, Grosshansdorf, Germany
[8] Univ Kiel, ARCN, German Ctr Lung Res DZL, Kiel, Germany
[9] Sanofi, Bridgewater, NJ USA
关键词
D O I
10.1183/13993003.congress-2022.2288
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
2288
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Long-term budesonide treatment of collagenous colitis: a randomised, double-blind, placebo-controlled trial
    Bonderup, O. K.
    Hansen, J. B.
    Teglbjaerg, P. S.
    Christensen, L. A.
    Fallingborg, J. F.
    GUT, 2009, 58 (01) : 68 - 72
  • [22] Long-term dupilumab effect on lung function in paediatric patients with uncontrolled asthma
    Bacharier, L. B.
    Zielen, S.
    Guilbert, T. W.
    Custovic, A.
    Altincatal, A.
    Ledanois, O.
    Gall, R.
    Sacks, H.
    Jacob-Nara, J. A.
    Deniz, Y.
    Rowe, P. J.
    KLINISCHE PADIATRIE, 2024, 236 (02): : S2 - S2
  • [23] Onercept for moderate-to-severe Crohn's disease: A randomized, double-blind, placebo-controlled trial
    Rutgeerts, Paul
    Sandborn, William J.
    Fedorak, Richard N.
    Rachmilewitz, Daniel
    Tarabar, Dino
    Gibson, Peter
    Nielsen, Ole Haagen
    Wild, Gary
    Schreiber, Stefan
    Rossi, Claudia Pena
    Zignani, Monia
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2006, 4 (07) : 888 - 893
  • [24] Long-term efficacy and safety of itolizumab in patients with moderate-to-severe chronic plaque psoriasis: A double-blind, randomized-withdrawal, placebo-controlled study
    Dogra, Sunil
    Krupashankar
    Budamakuntla, Leelavathy
    Srinivas, C. R.
    Khopkar, Uday
    Gupta, Sandesh
    Shetty, Narendra
    Pratap, Dasiga Venkata Subrahmanya
    Gopal, M. G.
    Rao, T. Narayana
    Garg, Vijay
    Sumathy, T. K.
    Saraswat, Abir
    Bhat, Ramesh
    Kura, Mahendra
    Pandey, Neeraj
    Shah, Radha
    Krishna, Kotla Sai
    Padmaja, Dalavai
    Manmohan, G.
    Ramakrishnan, M. S.
    Barve, Abhijit
    Montero, Enrique
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2015, 73 (02) : 331 - 333
  • [25] Effect of tezepelumab on airway inflammatory cells, remodelling, and hyperresponsiveness in patients with moderate-to-severe uncontrolled asthma (CASCADE): a double-blind, randomised, placebo-controlled, phase 2 trial (vol 9, pg 1299, 2021)
    Diver, S.
    Khalfaoui, L.
    Emson, C.
    LANCET RESPIRATORY MEDICINE, 2021, 9 (11): : E106 - E106
  • [26] Dupilumab Monotherapy in Adults with Moderate-to-Severe Atopic Dermatitis: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Study
    Bieber, Thomas R. M.
    Thaci, Diamant
    Graham, Neil
    Pirozzi, Gianluca
    Teper, Ariel
    Ren, Haobo
    Radin, Allen
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (02) : AB404 - AB404
  • [27] Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial
    Gibson, Peter G.
    Yang, Ian A.
    Upham, John W.
    Reynolds, Paul N.
    Hodge, Sandra
    James, Alan L.
    Jenkins, Christine
    Peters, Matthew J.
    Marks, Guy B.
    Baraket, Melissa
    Powell, Heather
    Taylor, Steven L.
    Leong, Lex E. X.
    Rogers, Geraint B.
    Simpson, Jodie L.
    LANCET, 2017, 390 (10095): : 659 - 668
  • [28] Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre, double-blind, randomised, placebo-controlled phase 2 trial
    Russell, Richard J.
    Chachi, Latifa
    FitzGerald, J. Mark
    Backer, Vibeke
    Olivenstein, Ronald
    Titlestad, Ingrid L.
    Ulrik, Charlotte Suppli
    Harrison, Timothy
    Singh, Dave
    Chaudhuri, Rekha
    Leaker, Brian
    McGarvey, Lorcan
    Siddiqui, Salman
    Wang, Millie
    Braddock, Martin
    Nordenmark, Lars H.
    Cohen, David
    Parikh, Himanshu
    Colice, Gene
    Brightling, Christopher E.
    LANCET RESPIRATORY MEDICINE, 2018, 6 (07): : 499 - 510
  • [29] Long-term cariprazine treatment for the prevention of relapse in patients with schizophrenia: A randomized, double-blind, placebo-controlled trial
    Durgam, Suresh
    Earley, Willie
    Li, Rui
    Li, Dayong
    Lu, Kaifeng
    Laszlovszky, Istvan
    Fleischhacker, W. Wolfgang
    Nasrallah, Henry A.
    SCHIZOPHRENIA RESEARCH, 2016, 176 (2-3) : 264 - 271
  • [30] Randomised, Placebo-Controlled, Double-Blind Study of Oral Tranexamic Acid in the Treatment of Moderate-to-Severe Melasma in an Australian Cohort
    Bala, Harini Rajgopal
    Nguyen, Jennifer
    Ross, Angelique
    Wong, Celestine
    Paul, Eldho
    Rodrigues, Michelle
    INDIAN JOURNAL OF DERMATOLOGY, 2022, 67 (04) : 454 - 458