Investigation of skin water loss and glycerol delivery through stratum corneum

被引：0
|
作者：
Genina, Elina A. [1 ]
Korobko, Anastasiya A. [1 ]
Bashkatov, Alexey N. [1 ]
Tuchin, Valery V. [1 ]
Yaroslavsky, Ilya V. [1 ]
Altshuler, Gregory B. [1 ]
机构：
[1] Saratov NG Chernyshevskii State Univ, Saratov, Russia
来源：
Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII | 2007年 / 6535卷
关键词：
D O I：
10.1117/12.740990
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Investigation of skin water loss and clearing agent delivery through stratum corneum is presented. Effectiveness of the method "lattice of islets of damage" for enhancement of stratum corneum permeability for water and 71% glycerol solution providing the skin clearing was investigated. Dehydration induced by both stimuli evaporation and osmotic agent action was studied by weight measurements. Measurements of refractive index dynamics of glycerol and water during its interaction with skin samples were carried out. The results have shown that proposed method allows effective transepidermal water loss and delivery of optical clearing agents.
引用
收藏
页码：G5351 / G5351
页数：8
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