A metal-organic cage-based nanoagent for enhanced photodynamic antitumor therapy

被引：9
|
作者：
Li, Wen-Yan [1 ]
Zhao, Chao-Wei [2 ]
Zhang, Yue-Feng [2 ]
Guan, Qun [1 ]
Wan, Jing-Jing [1 ]
Ma, Jian-Ping [1 ]
Li, Yan-An [1 ]
Dong, Yu-Bin [1 ]
机构：
[1] Shandong Normal Univ, Collaborat Innovat Ctr Functionalized Probes Chem, Coll Chem Chem Engn & Mat Sci, Key Lab Mol & Nano Probes,Minist Educ, Jinan 250014, Peoples R China
[2] Jiangxi Acad Sci, Inst Appl Chem, Nanchang 330096, Jiangxi, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 64期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1039/d1cc02629a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, we report, for the first time, a Pd6L8(NO3)(5.4)(ICG)(6.6) (ICG = indocyanine green) cage-based hexagonal nanoplate (3) via a combined nanoprecipitation and solid-state anion-exchange approach. Nanoplate 3 possesses enhanced near-infrared (NIR) light-triggered O-1(2) generation, high cellular uptake selective lysosome-targeting ability, and, consequently, excellent antineoplastic activity.
引用
收藏
页码：7954 / 7957
页数：4
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