Cancer stem cells: A new target for cancer therapy

被引：9
|
作者：
Li, Qianhui
Wu, Jiayu
Chen, Shuo
Zhao, Yang
机构：
[1] Guangzhou Med Univ, Affiliated Hosp 3, Dept Obstet & Gynecol, Key Lab Major Obstet Dis Guangdong Prov, Guangzhou, Guangdong, Peoples R China
[2] Guangdong Higher Educ Inst Guangdong Prov, Key Lab Reprod & Genet, Guangzhou, Guangdong, Peoples R China
来源：
HISTOLOGY AND HISTOPATHOLOGY | 2018年 / 33卷 / 12期
基金：
中国国家自然科学基金;
关键词：
Cancer stem cells; Identification and isolation; Regulatory pathway; Targeted therapy; OVARIAN-CANCER; HEPATOCELLULAR-CARCINOMA; PANCREATIC-CANCER; GLIOBLASTOMA; TUMORS; GROWTH; LINE; IDENTIFICATION; SUBPOPULATION; POPULATION;
D O I：
10.14670/HH-18-004
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The introduction of the theory of cancer stem cells (CSCs) has provided a new direction and perspective for our understanding of the nature and origin of tumors. Cancer stem cells are believed to be responsible for the treatment failure, drug tolerance, metastasis, and recurrence of tumors. However, it remains a challenge to identify or isolate tumor stem cells and determine their regulatory mechanisms. Therefore, further understanding of the biological characteristics and functions of CSCs is of great practical significance and value to develop new methods of tumor diagnosis and treatment, and may bring new hope patients with cancer.
引用
收藏
页码：1247 / 1252
页数：6
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