On conformational transitions in myosin cross-bridges during the mechanochemical act

被引：0
|
作者：
Pirtskhalava, MK [1 ]
Zaalishvili, MM [1 ]
机构：
[1] Georgian Acad Sci, Inst Mol Biol & Biol Phys, GE-380060 Tbilisi 60, Georgia
来源：
BIOFIZIKA | 1998年 / 43卷 / 03期
关键词：
myosin bridges; conformational transitions; mechanochemical act;
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
The investigations of the molecular bases of muscle contraction posed the following question: in which part of the myosin cross-bridge, the head or the fibrillar part, the conformational changes occur that lead to the generation of force. The paper deals with experimental and theoretical data that are in some way related to the solution of this question. Based on the analysis of recent data, an alternative pattern of ATP hydrolysis-coupled structural alternations in the myosin bridge during the mechanochemical act is proposed.
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页码：490 / 495
页数：6
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