Abdominal aortic aneurysm;
Nonruptured aneurysm;
Vascular surgery;
Open versus endovascular repair;
NSQIP;
Mortality;
VS. OPEN REPAIR;
CLINICAL-TRIAL;
EVAR TRIAL;
OUTCOMES;
METAANALYSIS;
GENDER;
D O I:
10.1016/j.jss.2017.03.061
中图分类号:
R61 [外科手术学];
学科分类号:
摘要:
Background: Age is a well-known risk factor for postoperative death in patients with abdominal aortic aneurysms (AAA), and the efficacy of open aneurysm repair (OAR) and endovascular aneurysm repair (EVAR) remains controversial in the elderly population. The aim of this study was to determine the predictors of 30-d mortality after AAA repair in elderly population. Methods: Using the National Surgical Quality Improvement Program vascular-targeted database (2011-2014), we identified all patients aged >70 y who underwent OAR and EVAR for nonruptured AAA. Univariate and multivariable logistic regression analyses were implemented to examine postoperative mortality adjusting for patient demographics and characteristics. Results: A total of 4229 nonruptured AAA repairs were performed (OAR: 360 [8.5%] versus EVAR: 3869 [91.5%]). Most patients were males (79 %) and White (81%) with a mean age of 78 +/- 6 y. Obesity was more prevalent in EVAR group (31% versus 24%, P = 0.008). Whereas, smoking was more likely to be seen in patients undergoing an OAR (35% versus 22%, P < 0.001). The 30-d mortality was significantly higher after OAR versus EVAR (8% versus 2%, P < 0.001). After adjusting, OAR was associated with almost five times higher mortality than EVAR (adjusted odds ratio: 4.88; 2.85-8.34, P < 0.001). Conclusions: This study reflects contemporary real world outcomes of nonruptured AAA repair in the elderly. Open repair was associated with almost fivefold increase in mortality compared with endovascular repair. Elderly patients who are functionally dependent are less likely to benefit from AAA repair, whether OAR or EVAR. Further prospective studies are required to better understand the predictors of mortality after AAA repair in the geriatric population which could guide decision-making and improve outcomes in this population. (C) 2017 Elsevier Inc. All rights reserved.
机构:
Beth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
Schermerhorn, Marc L.
Giles, Kristina A.
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机构:
Beth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
Giles, Kristina A.
Sachs, Teviah
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Beth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
Sachs, Teviah
Bensley, Rodney P.
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Beth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
Bensley, Rodney P.
O'Malley, A. James
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Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 USABeth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
O'Malley, A. James
Cotterill, Philip
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Ctr Medicare Serv, Boston, MA USA
Ctr Medicaid Serv, Boston, MA USABeth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
Cotterill, Philip
Landon, Bruce E.
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机构:
Beth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA
Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 USABeth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
机构:
Beth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USA
Harvard Med Sch, Massachusetts Gen Hosp, Dept Surg, Boston, MA USABeth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USA
Deery, Sarah E.
O'Donnell, Thomas F. X.
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机构:
Beth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USA
Harvard Med Sch, Massachusetts Gen Hosp, Dept Surg, Boston, MA USABeth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USA
O'Donnell, Thomas F. X.
Bodewes, Thomas C. F.
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Beth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USA
Bodewes, Thomas C. F.
Dalebout, Barbara A.
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Beth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USA
Dalebout, Barbara A.
Pothof, Alexander B.
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Beth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USA
Pothof, Alexander B.
Shean, Katie E.
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Beth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USA
Shean, Katie E.
Darling, Jeremy D.
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机构:
Beth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USA
Darling, Jeremy D.
Schermerhorn, Marc L.
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机构:
Beth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Div Vasc & Endovasc Surg, Boston, MA 02215 USA
机构:
Beth Israel Deaconess Med Ctr, 110 Francis St,Suite 5B, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, 110 Francis St,Suite 5B, Boston, MA 02215 USA
Deery, Sarah E.
Schermerhorn, Marc L.
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Beth Israel Deaconess Med Ctr, 110 Francis St,Suite 5B, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, 110 Francis St,Suite 5B, Boston, MA 02215 USA